Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516271 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL17815907 | 0.76 | CDK8 (0.39) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL3758060 | 0.73 | L3MBTL1 (0.37) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL16061286 | 0.72 | PIK3CG (0.45) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL21816236 | 0.70 | EGLN2 (0.34) | HPGDHSD17B10FLT1CDK8CDK9 | |
| SCHEMBL17812872 | 0.70 | FLT1 (0.35) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL12618988 | 0.70 | PDE4A (0.39) | KDM4EALDH1A1HPGDHSD17B10FLT1 | |
| Hydrochloric Acid SCHEMBL1795034 | 0.69 | CYP3A4 (0.40) | HPGDHSD17B10FLT1CDK8CDK9 | |
| SCHEMBL3754494 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAFLT1CDK8 | |
| SCHEMBL12618998 | 0.66 | PDE4A (0.47) | HPGDHSD17B10MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | KDM4E 4532/4885ALDH1A1 3358/4885HPGD 768/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | KDM4E 4532/4885ALDH1A1 3358/4885HPGD 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.