Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | MC5R | P33032 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL23237 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL3789760 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL29509878 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| SCHEMBL827403 | 0.75 | RAB9A (0.67) | ALDH1A1HSD17B10TDP1HPGDNPC1 | |
| 2-Mercaptobenzothiazole SCHEMBL10429471 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL78798 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL17684719 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL7640197 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL20537310 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 | |
| 2-Mercaptobenzothiazole SCHEMBL11575316 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1ADRA2AFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113888-A1 | LUBRICATING OIL ADDITIVE COMPOSITION AND METHOD OF MAKING THE SAME | CHEVRON ORONITE COMPANY LLC | 2008-05-15 | — | — | US | claimed |
| US-10988854-B2 | Flexible color adjustment for dark Cr(III) platings | MACDERMID ENTHONE INC. (US) | 2021-04-27 | — | — | US | disclosed |
| US-20200141022-A1 | FLEXIBLE COLOR ADJUSTMENT FOR DARK Cr(III) PLATINGS | MACDERMID ENTHONE INC. (US) | 2020-05-07 | — | — | US | disclosed |
| EP-2190829-A2 | AMIDINE, THIOUREA AND GUANIDINE DERIVATIVES OF 2-AMINOBENZOTHIAZOLES AND AMINOBENZOTHIAZINES FOR THEIR USE AS PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE PATHOLOGIES | Rottapharm S.p.A. (IT) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009040331-A2 | AMIDINE, THIOUREA AND GUANIDINE DERIVATIVES OF 2-AMINOBENZOTHIAZOLES AND AMINOBENZOTHIAZINES FOR THEIR USE AS PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE PATHOLOGIES | ROTTAPHARM S.P.A. (IT) | 2009-04-02 | — | — | WO | disclosed |