Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | BCL3 | P20749 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15236976 | 0.99 | ALDH1A1 (0.50) | ALDH1A1NPC1POLBDRD4BCL3 | |
| SCHEMBL9017973 | 0.81 | POLB (0.51) | ALDH1A1NPC1POLBRBP4GAA | |
| SCHEMBL4082876 | 0.80 | ALDH1A1 (0.35) | ALDH1A1NPC1POLBDRD4BCL3 | |
| SCHEMBL18397975 | 0.79 | POLB (0.52) | ALDH1A1NPC1POLBRBP4DGAT2 | |
| SCHEMBL3762834 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPC1POLBRBP4DGAT2 | |
| SCHEMBL3752774 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NPC1POLBRBP4DGAT2 | |
| SCHEMBL27335141 | 0.77 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBRBP4DGAT2 | |
| SCHEMBL29944078 | 0.76 | RBP4 (0.64) | NPC1POLBRBP4NAMPTHPGD | |
| SCHEMBL8569196 | 0.76 | ALDH1A1 (0.61) | ALDH1A1NPC1POLBRBP4DGAT2 | |
| SCHEMBL6776473 | 0.75 | NPC1 (0.59) | ALDH1A1NPC1POLBRBP4DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | claimed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | claimed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | claimed |
| US-7655677-B2 | Composition and method for controlling house insect pest | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-02-02 | — | — | US | disclosed |
| US-20080200522-A1 | COMPOSITION AND METHOD FOR CONTROLLING HOUSE INSECT PEST | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| US-7195773-B2 | Such as N-cyanomethyl-4-trifluoromethyl-3-pyridinecarboxyamide | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20050215597-A1 | Composition for controlling house insect pest and method for controlling house insect pest | ISHIHARA SANGYO KAISHA, LTD (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1328154-B1 | PESTICIDAL COMPOSITION | ISHIHARA SANGYO KAISHA (JP) | 2005-07-27 | — | — | EP | disclosed |
| EP-1476017-A2 | COMPOSITION AND METHOD FOR CONTROLLING HOUSE INSECT PEST | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040024026-A1 | Pesticidal composition | ISHIHARA SANGYO KAISHA, LTD (JP) | 2004-02-05 | — | — | US | disclosed |
| WO-2003069990-A2 | COMPOSITION AND METHOD FOR CONTROLLING HOUSE INSECT PEST | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-08-28 | — | — | WO | disclosed |
| EP-1328154-A1 | PESTICIDAL COMPOSITION | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034050-A1 | PESTICIDAL COMPOSITION | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200522-A1 | COMPOSITION AND METHOD FOR CONTROLLING HOUSE INSECT PEST | DDT, ACHE, BCHE | ALDH1A1 3596/4885NPC1 4127/4885POLB 4173/4885 |
| US-20040024026-A1 | Pesticidal composition | PRDX1, DDT, PRDX6 | ALDH1A1 911/4885NPC1 4369/4885POLB 2660/4885 |
| US-20050215597-A1 | Composition for controlling house insect pest and method for controlling house insect pest | DDT, PHB1, ACHE | ALDH1A1 3702/4885NPC1 3918/4885POLB 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.