Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613807 | 0.87 | HDAC4 (0.66) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL2989515 | 0.87 | HDAC4 (0.66) | HDAC4HDAC7HDAC5EGFRSRC | |
| Hydrochloric Acid SCHEMBL2982836 | 0.85 | HDAC4 (0.64) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL2990607 | 0.84 | HDAC4 (0.50) | HDAC4HDAC7HDAC5EGFRSRC | |
| Biphenyl SCHEMBL2987647 | 0.82 | HDAC4 (0.60) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL3772600 | 0.81 | HDAC4 (0.55) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL3769074 | 0.81 | HDAC4 (0.44) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL3775603 | 0.78 | HDAC4 (0.36) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL3768847 | 0.78 | EGFR (0.37) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL6024230 | 0.74 | HDAC4 (0.42) | HDAC4HDAC7HDAC5EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10722882-B2 | Chemiluminescent and fluorescent substrate pads and uses thereof | PIERCE BIOTECHNOLOGY, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20180043355-A1 | CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF | PIERCE BIOTECHNOLOGY, INC. | 2018-02-15 | — | — | US | disclosed |
| US-8822233-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | GIRI BRIJ PAL (US) | 2014-09-02 | — | — | US | disclosed |
| US-20140121362-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-05-01 | — | — | US | disclosed |
| US-20140088297-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140073771-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-03-13 | — | — | US | disclosed |
| US-8546150-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | Michigan Diagnostics, L.L.C. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546150-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | Michigan Diagnostics, L.L.C. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20100317122-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317877-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317031-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317122-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317877-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317031-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-7781229-B2 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088297-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | HDAC4 4737/4885HDAC7 4724/4885HDAC5 4405/4885 |
| US-20140121362-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | HDAC4 4737/4885HDAC7 4724/4885HDAC5 4405/4885 |
| US-20100317877-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | HDAC4 4679/4885HDAC7 4639/4885HDAC5 4344/4885 |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | BTD, DDT, LPO | HDAC4 4743/4885HDAC7 4734/4885HDAC5 4247/4885 |
| US-20100317031-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | HDAC4 4705/4885HDAC7 4671/4885HDAC5 4366/4885 |
| US-20100317122-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, LPO | HDAC4 4658/4885HDAC7 4616/4885HDAC5 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.