Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023309 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TRPA1MAPK1HIF1ACYP11B2 | |
| SCHEMBL3661934 | 0.90 | NFE2L2 (0.41) | ALDH1A1TRPA1MAPK1HIF1ACYP11B2 | |
| SCHEMBL3768756 | 0.90 | NFE2L2 (0.41) | ALDH1A1TRPA1MAPK1HIF1ACYP11B2 | |
| SCHEMBL3776287 | 0.89 | NFE2L2 (0.38) | TRPA1NFE2L2GAA | |
| SCHEMBL3662395 | 0.89 | NFE2L2 (0.38) | TRPA1NFE2L2GAA | |
| SCHEMBL3769358 | 0.85 | TRPA1 (0.39) | ALDH1A1TRPA1LMNAABCG2MEN1 | |
| SCHEMBL3664523 | 0.85 | TRPA1 (0.39) | ALDH1A1TRPA1LMNAABCG2MEN1 | |
| SCHEMBL3762718 | 0.83 | MDM2 (0.40) | ALDH1A1TRPA1NFE2L2MEN1KMT2A | |
| SCHEMBL3662246 | 0.83 | MDM2 (0.40) | ALDH1A1TRPA1NFE2L2MEN1KMT2A | |
| SCHEMBL3662379 | 0.83 | ABCG2 (0.46) | ALDH1A1NFE2L2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220455-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them | BASF SE (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20090305887-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them | BASF SE (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090305887-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them | CBR3, PFAS, CBR1 | ALDH1A1 559/4885TRPA1 272/4885MAPK1 1999/4885 |
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, NOX5, TET1 | ALDH1A1 20/4885TRPA1 2075/4885MAPK1 3255/4885 |
| US-20120220455-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them | CBR3, PFAS, CBR1 | ALDH1A1 559/4885TRPA1 272/4885MAPK1 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.