SCHEMBL3771334

SCHEMBL3771334

c1ncnc(CC2CO2)n1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CYP3A4 P08684 1/20 0.32
HIF1A Q16665 1/20 0.32
HSP90AA1 P07900 1/20 0.31
GLA P06280 1/20 0.31
HBB P68871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204764 0.80 MEN1 (0.32) TDP1ALDH1A1
SCHEMBL9419598 0.74 ALDH1A1 (0.36) TDP1ALDH1A1TP53SMN1; SMN2HBB
SCHEMBL4860246 0.71
SCHEMBL6531076 0.66 MAP4K4 (0.33) CYP3A4HSP90AA1
SCHEMBL11205105 0.65 ALDH1A1 (0.36) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL2014742 0.64 ALDH1A1 (0.36) TDP1ALDH1A1TP53SMN1; SMN2HBB
SCHEMBL131333 0.64 TDP1 (0.38) TDP1ALDH1A1TP53TSHRSMN1; SMN2
SCHEMBL132428 0.64 ALDH1A1 (0.37) TDP1ALDH1A1TP53TSHRSMN1; SMN2
SCHEMBL6480647 0.60 TDP1 (0.45) TDP1ALDH1A1TP53TSHRSMN1; SMN2
SCHEMBL3141903 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022203649-A1 TEXTILE COATING COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-09-29 WO claimed
US-7847026-B2 Epoxy resins adducted with reactive liquid rubber having improved low temperature performance properties EMERALD SPECIALTY POLYMERS, LLC. (US) 2010-12-07 US claimed
US-20090318636-A1 Epoxy resins adducted with reactive liquid rubber having improved low temperature performance properties EMERALD SPECIALTY POLYMERS, LLC. (US) 2009-12-24 US claimed
WO-2009051699-A1 AMINE TERMINATED TOUGHENERS FOR EPOXY RESIN BASED ADHESIVES AND MATERIALS EMERALD SPECIALTY POLYMERS, LLC (US) 2009-04-23 WO claimed
US-20090099312-A1 Amine terminated tougheners for epoxy resin based adhesives and materials EMERALD SPECIALTY POLYMERS, LLC. 2009-04-16 US claimed
US-5157077-A Carboxyl, amine or epoxy-terminated reactive polymers THE B. F. GOODRICH COMPANY (US) 1992-10-20 US claimed
CN-111886266-B Thermoplastic acrylic resin, process for producing the same, and resin composition 株式会社钟化 2023-05-23 CN disclosed
WO-2022203649-A1 TEXTILE COATING COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-09-29 WO disclosed
CN-111886266-A Thermoplastic acrylic resin, process for producing the same, and resin composition 株式会社钟化 2020-11-03 CN disclosed
CN-111164512-A Photosensitive resin composition, cured film, element provided with cured film, organic EL display, and method for manufacturing organic EL display 东丽株式会社 2020-05-15 CN disclosed
WO-2019187404-A1 THERMOPLASTIC ACRYLIC RESIN AND METHOD FOR PRODUCING SAME, AND RESIN COMPOSITION 株式会社カネカ 2019-10-03 WO disclosed
CN-104039902-B Curable coating composition 阿克佐 诺贝尔国际涂料股份有限公司 2016-10-26 CN disclosed
CN-104039902-A Curable coating composition AKZO NOBEL COATINGS INT BV 2014-09-10 CN disclosed
CN-102224205-A Wear and impact resistant reflective road lane markers DOW GLOBAL TECHNOLOGIES INC 2011-10-19 CN disclosed
EP-1203054-B1 POLYMER BLENDS WITH IMPROVED IMPACT RESISTANCE CIBA SC HOLDING AG (CH) 2004-11-03 EP disclosed
US-6765062-B2 1) POLYPHENYLENE ETHER OR POLYSTYRENE, 2) POLYMER CONTAINING AMINE OR CARBOXYLIC ACID END GROUPS, (POLYESTER OR POLYAMIDE) AND 3) ADDITION POLYMER PREPARED USING A GLYCIDYL-FUNCTIONALIZED NITROXYL INITIATOR. CIBA SPECIALTY CHEMICALS CORPORATION 2004-07-20 US disclosed
US-20030088027-A1 Polymer blends with improved impact resistance CHIN HUI (US) 2003-05-08 US disclosed
US-6444754-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-03 US disclosed
EP-1203054-A1 POLYMER BLENDS WITH IMPROVED IMPACT RESISTANCE Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
WO-2001012721-A1 POLYMER BLENDS WITH IMPROVED IMPACT RESISTANCE CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2001-02-22 WO disclosed