Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 4/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726389 | 0.98 | MEN1 (0.61) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL4016088 | 0.96 | MEN1 (0.59) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL2326546 | 0.95 | MEN1 (0.58) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL27504393 | 0.93 | MEN1 (0.56) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL3101290 | 0.84 | SNCA (0.60) | KDM4ETSHRHSD17B10SNCALMNA | |
| SCHEMBL836622 | 0.84 | SNCA (0.60) | KDM4ETSHRHSD17B10SNCALMNA | |
| SCHEMBL4016326 | 0.84 | SNCA (0.49) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL5352921 | 0.82 | SNCA (0.51) | MEN1KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL10497952 | 0.82 | PKM (0.64) | L3MBTL1KDM4ELMNAHTTPTGS2 | |
| SCHEMBL300937 | 0.82 | SNCA (0.62) | KDM4ETSHRHSD17B10SNCALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435978-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20100324009-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20100317644-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-1085540-B1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | SHOWA DENKO KK (JP) | 2009-07-01 | — | — | EP | disclosed |
| EP-1158551-B1 | SOLID ELECTROLYTIC CAPACITOR AND ITS PRODUCTION METHOD | SHOWA DENKO KK (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| EP-1811532-A2 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-07-25 | — | — | EP | disclosed |
| EP-1190426-B1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING THE SAME | SHOWA DENKO KK (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-20060217362-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2006-09-28 | — | — | US | disclosed |
| US-20060179627-A1 | Valve acting metal having pores, dielectric film formed on surface, and electroconductive polythiophene as solid electrolyte provided on dielectric film; improved moisture/heat/thermal stess resistance | SHOWA DENKO K.K. | 2006-08-17 | — | — | US | disclosed |
| US-20030148023-A1 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO K.K. | 2003-08-07 | — | — | US | disclosed |
| US-6517892-B1 | Forming electroconductive film filling microfine pores and covering dielectric layer; oxidative solution polymerization; such as cationic polythiophene or polyfuran | SHOWA DENKO K.K. (JP) | 2003-02-11 | — | — | US | disclosed |
| US-6466421-B1 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO K.K. (JP) | 2002-10-15 | — | — | US | disclosed |
| US-20020105777-A1 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO K.K. | 2002-08-08 | — | — | US | disclosed |
| US-6381121-B1 | Solid electrolytic capacitor | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-1190426-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING THE SAME | Showa Denko K K (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6344966-B1 | ELECTRICALLY CONDUCTING POLYMER LAYER CONTAINS AS A DOPANT AN ANION OF(1) ALKOXY-SUBSTITUTED NAPHTHALENESULFONATE, (2) A HETEROCYCLIC SULFONATE, OR (3) AN ANION OF AN ALIPHATIC POLYCYCLIC COMPOUND | SHOWA DENKO K.K. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1158551-A1 | SOLID ELECTROLYTIC CAPACITOR AND ITS PRODUCTION METHOD | Showa Denko K K (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-1085540-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | Showa Denko K K (JP) | 2001-03-21 | — | — | EP | disclosed |
| WO-2000060620-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING THE SAME | SHOWA DENKO K. K. (JP) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317644-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | MEN1 4354/4885KMT2A 1686/4885L3MBTL1 4648/4885 |
| US-20100324009-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | MEN1 4354/4885KMT2A 1686/4885L3MBTL1 4648/4885 |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | SULT2A1, STS, SULT1A1 | MEN1 4354/4885KMT2A 1686/4885L3MBTL1 4648/4885 |
| US-20060217362-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | MEN1 998/4885KMT2A 4104/4885L3MBTL1 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.