Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771904 | 0.86 | APP (0.55) | APPSNCAALDH1A1KDM4EMEN1 | |
| SCHEMBL3777988 | 0.86 | RAB9A (0.55) | ALDH1A1KDM4EMEN1KMT2AALPL | |
| SCHEMBL3776968 | 0.75 | ALDH1A1 (0.68) | APPSNCAALDH1A1KDM4EMEN1 | |
| SCHEMBL327849 | 0.75 | APP (0.63) | APPSNCAALDH1A1KDM4EMEN1 | |
| SCHEMBL532189 | 0.74 | APP (0.55) | APPSNCAALDH1A1KDM4EMEN1 | |
| SCHEMBL24767122 | 0.72 | APP (0.53) | APPSNCAALDH1A1KDM4EMEN1 | |
| SCHEMBL3774405 | 0.71 | APP (0.58) | APPALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2614903 | 0.71 | KDM4E (0.58) | ALDH1A1KDM4EMEN1KMT2AALPL | |
| Alcohol SCHEMBL6810203 | 0.70 | APP (0.86) | APPSNCAMEN1KMT2APOLB | |
| SCHEMBL8066 | 0.70 | APP (1.00) | APPSNCAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003625-A1 | AMINOPHENOXAZINONE AS AN ANTI-TUMOUR AND ANTI-INFLAMMATORY AGENT | EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKILINIKUM (DE) | 2009-01-08 | — | — | WO | claimed |
| US-20100324285-A1 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2098228-A1 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2009-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324285-A1 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT | PTGES2, PTGS2, PTGES | APP 920/4885SNCA 3459/4885ALDH1A1 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.