SCHEMBL377472

SCHEMBL377472

CC(C)C(C)CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)CC=C(O)[C@@]45C[C@@]35CC[C@]12C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ACLY P53396 2/20 0.38
▸ ACACA Q13085 2/20 0.38
▸ HSD11B1 P28845 5/20 0.37
▸ EP300 Q09472 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ PTPN11 Q06124 1/20 0.34
▸ EBP Q15125 3/20 0.33
▸ ESR2 Q92731 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HSD11B2 P80365 1/20 0.32
▸ TOP2A P11388 4/20 0.31
▸ TOP2B Q02880 4/20 0.31
▸ PRKAG1 P54619 1/20 0.31
▸ PRKAA2 P54646 1/20 0.31
▸ PRKAB1 Q9Y478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159792 0.88 EBP (0.47) ACLYACACAHSD11B1PTPN11EBP
SCHEMBL464758 0.87 HSD11B1 (0.49) ACLYACACAHSD11B1PTGS1PTGS2
SCHEMBL6341662 0.83 HSD11B1 (0.45) ACLYACACAHSD11B1PTGS1PTGS2
SCHEMBL10635071 0.77 HSD11B1 (0.40) ACLYACACAHSD11B1PTGS1PTGS2
Niacin SCHEMBL6684757 0.76 EBP (0.39) ACLYACACAHSD11B1PTGS1PTGS2
SCHEMBL1874653 0.74 ACLY (0.48) ACLYACACAHSD11B1EP300PTGS1
SCHEMBL2257958 0.73 EBP (0.45) ACLYACACAHSD11B1EBPPRKAG1
SCHEMBL12634185 0.72 ACLY (0.67) ACLYACACAHSD11B1EP300PTGS1
SCHEMBL29510985 0.72 ACLY (0.67) ACLYACACAHSD11B1EP300PTGS1
SCHEMBL10349517 0.70 EBP (0.39) ACLYACACAHSD11B1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3236310-A — — None — — JP disclosed
EP-2377874-B1 Compositions comprising a lophenol MORINAGA MILK INDUSTRY CO LTD (JP) 2019-01-23 — — EP disclosed
US-9592264-B2 Delivery system for saw palmetto extract and carotenoid U.S. Nutraceuticals, LLC (US) 2017-03-14 — — US disclosed
US-20140302136-A1 DELIVERY SYSTEM FOR SAW PALMETTO EXTRACT AND CAROTENOID U.S. NUTRACEUTICALS, LLC D/B/A VALENSA INTERNATIONAL (US) 2014-10-09 — — US disclosed
WO-2014165561-A2 DELIVERY SYSTEM FOR SAW PALMETTO EXTRACT AND CAROTENOID U.S. NUTRACEUTICALS, LLC D/B/A VALENSA INTERNATIONAL (US) 2014-10-09 — — WO disclosed
US-8470807-B2 Antioxidant MORINAGA MILK INDUSTRY CO., LTD. (JP) 2013-06-25 — — US disclosed
EP-1343860-B1 A PROCESS FOR PREPARING VEGETABLE OIL FRACTIONS RICH IN NON-TOCOLIC, HIGH-MELTING, UNSAPONIFIABLE MATTER AARHUSKARLSHAMN DENMARK AS (DK) 2012-01-25 — — EP disclosed
EP-2377874-A1 ANTIOXIDANT Morinaga Milk Industry Co., Ltd. (JP) 2011-10-19 — — EP disclosed
US-20110212931-A1 ANTIOXIDANT MORINAGA MILK INDUSTRY CO., LTD. (JP) 2011-09-01 — — US disclosed
CN-101098702-B Drugs, food or drink for improving pancreatic functions MORINAGA MILK INDUSTRY CO LTD 2010-12-29 — — CN disclosed
WO-2002050221-A1 A PROCESS FOR PREPARING VEGETABLE OIL FRACTIONS RICH IN NON-TOCOLIC, HIGH-MELTING, UNSAPONIFIABLE MATTER AARHUS OLIEFABRIK A/S (DK) 2002-06-27 — — WO disclosed
EP-1146798-A2 MODIFIED FOOD PRODUCTS AND BEVERAGES, AND ADDITIVES FOR FOOD AND BEVERAGES Nutrahealth Ltd. (UK) (GB) 2001-10-24 — — EP disclosed
US-20010008638-A1 NUTRITIONAL SUPPLEMENT COMPRISING AT LEAST ONE PROHORMONE AND AT LEAST ONE ANTI-ESTROGEN COMPOUND IN A TIME-RELEASE DOSAGE FORM KAIZEN, INC. 2001-07-19 — — US disclosed
WO-2001039656-A2 METHOD OF MEDICAL MANAGEMENT FOR LOWER URINARY TRACT SYMPTOMS AND BENIGN PROSTATIC HYPERPLASIA STARCOR PHARMACEUTICALS, INC. (US) 2001-06-07 — — WO disclosed
US-6200573-B1 Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia STARCOR PHARMACEUTICALS, INC. 2001-03-13 — — US disclosed
WO-2000041491-A2 MODIFIED FOOD PRODUCTS AND BEVERAGES, AND ADDITIVES FOR FOOD AND BEVERAGES NUTRAHEALTH LTD (UK) (GB) 2000-07-20 — — WO disclosed
US-5972345-A COMPRISING SAW PALMETTO EXTRACT, AFRICAN PYGEUM EXTRACT, STINGING NETTLE EXTRACT CHIZICK STEPHEN (CA) 1999-10-26 — — US disclosed
EP-0914329-A2 METHOD OF MANUFACTURING AN ESTER MIXTURE UNILEVER N.V. (NL) 1999-05-12 — — EP disclosed
WO-1998001126-A2 METHOD OF MANUFACTURING A STEROL ESTER MIXTURE UNILEVER N.V. (NL) 1998-01-15 — — WO disclosed
JP-H03236310-A HAIR TONIC NONOGAWA SHOJI:KK 1991-10-22 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212931-A1 ANTIOXIDANT GPX4, GPX1, LPO ACLY 2017/4885ACACA 382/4885HSD11B1 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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