SCHEMBL3775182

SCHEMBL3775182

NS(=O)(=O)c1ccc(C(F)(F)F)cc1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.46
PTGES2 Q9H7Z7 7/20 0.42
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 3/20 0.42
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
CA12 O43570 2/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
LMNA P02545 1/20 0.40
AR P10275 1/20 0.40
KMT2A Q03164 1/20 0.39
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684584 0.79 CA1 (0.55) KIF11PTGES2CA1CA2CA9
SCHEMBL30918492 0.79 KIF11 (0.47) KIF11PTGES2CA1CA2CA9
SCHEMBL29458370 0.79 PDIA6 (0.49) KIF11PTGES2CA1CA2CA9
SCHEMBL2183059 0.79 KIF11 (0.47) KIF11PTGES2CA1CA2CA9
SCHEMBL30137559 0.79 CA1 (0.55) KIF11PTGES2CA1CA2CA9
SCHEMBL9048102 0.79 CA1 (0.55) KIF11PTGES2CA1CA2CA9
SCHEMBL6191403 0.79 PDIA6 (0.49) KIF11PTGES2CA1CA2CA9
SCHEMBL6038959 0.78 KIF11 (0.49) KIF11PTGES2CA1CA2CA9
SCHEMBL4183675 0.77 ALOX5AP (0.43) KIF11CA1CA2ALOX5APFEN1
SCHEMBL18985068 0.76 CA1 (0.55) KIF11PTGES2CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP claimed
US-7855166-B2 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2010-12-21 US disclosed
CN-101166724-A Sulfonylamino (thio) carbonyl compounds in the form of herbicides or plant growth regulators BAYER CROPSCIENCE AG (DE) 2008-04-23 CN disclosed
EP-1877380-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2008-01-16 EP disclosed
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2006-11-16 US disclosed
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP disclosed
WO-2006114221-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds TST, CBR3, MYB KIF11 3933/4885PTGES2 2029/4885CA1 4582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.