Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.63 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CFD | P00746 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767067 | 0.92 | KCNK3 (0.70) | KCNK3KCNK9PPARGPTGS1RXFP1 | |
| SCHEMBL3780032 | 0.88 | KCNK3 (0.60) | KCNK3KCNK9SENP1PPARGPTGS1 | |
| SCHEMBL7605581 | 0.85 | SENP1 (0.59) | SENP1PPARGCHRM3SENP2RXFP1 | |
| SCHEMBL3768813 | 0.84 | KCNK3 (0.61) | KCNK3KCNK9PTGS1RXFP1HTT | |
| SCHEMBL3766559 | 0.84 | KCNK3 (0.66) | KCNK3KCNK9PTGS1RXFP1PTGES | |
| SCHEMBL3770493 | 0.81 | KCNK3 (0.60) | KCNK3KCNK9PTGS1RXFP1PTGES | |
| SCHEMBL3769343 | 0.80 | LMNA (0.70) | KCNK3KCNK9PPARGPTGS1RXFP1 | |
| SCHEMBL3771423 | 0.80 | KCNK3 (0.61) | KCNK3KCNK9PTGS1RXFP1PTGES | |
| SCHEMBL3769394 | 0.80 | KCNK3 (0.64) | KCNK3KCNK9PPARGPTGS1RXFP1 | |
| SCHEMBL3766556 | 0.79 | KCNK3 (0.82) | KCNK3KCNK9PPARGPTGS1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | KCNK3 1692/4885KCNK9 1283/4885SENP1 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.