Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785844 | 0.83 | MPO (0.43) | SQORTSHRHSD17B10 | |
| SCHEMBL3776179 | 0.78 | MPO (0.39) | NPC1HTTRAB9ASMN1; SMN2SQOR | |
| SCHEMBL3787051 | 0.76 | MEN1 (0.39) | SMN1; SMN2SQORMAPTMEN1KMT2A | |
| SCHEMBL3787119 | 0.76 | KCNH3 (0.39) | HTTRAB9AHSD17B10MAPTMEN1 | |
| SCHEMBL3782859 | 0.74 | KCNH3 (0.47) | — | |
| SCHEMBL3713217 | 0.74 | KCNH3 (0.41) | HTTMAPT | |
| SCHEMBL3782046 | 0.73 | MPO (0.45) | SMN1; SMN2TSHRHSD17B10MAPTTP53 | |
| SCHEMBL3782854 | 0.72 | NPSR1 (0.39) | — | |
| SCHEMBL3783407 | 0.70 | CA1 (0.42) | MAPTTP53GAA | |
| SCHEMBL3779747 | 0.69 | MPO (0.38) | NPC1HTTRAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083645-A1 | PYRIMIDO[5,4-e][1,2,4]TRIAZINES AND USES THEREOF | SHANGHAI TARGETDRUG CO., LTD (CN) | 2010-07-29 | — | — | WO | disclosed |