SCHEMBL3776327

SCHEMBL3776327

CCCCN(CCCC)C(C)C(C)=C(C)[SiH3]

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3781816 0.87 FDPS (0.35)
SCHEMBL3765343 0.78 PGR (0.35)
SCHEMBL3768614 0.78 MMP1 (0.31) MMP1MMP2MMP3MMP8
SCHEMBL3772471 0.71 CA12 (0.30)
SCHEMBL28856644 0.70 MMP1 (0.42) MMP1MMP2MMP3MMP8
SCHEMBL28856645 0.70 MMP1 (0.42) MMP1MMP2MMP3MMP8
SCHEMBL19882090 0.69 GGPS1 (0.41) MMP1MMP2MMP3MMP8
SCHEMBL28847191 0.68 CA1 (0.42) MMP1MMP2MMP3MMP8
SCHEMBL27131531 0.67 MMP1 (0.33) MMP1MMP2MMP3MMP8
SCHEMBL331155 0.67 MMP1 (0.38) MMP1MMP2MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436166-B2 Amino-containing vinylsilane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-07 US disclosed
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD BHMT2, GNMT, VASP MMP1 4532/4885MMP2 4402/4885MMP3 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.