Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865337 | 0.84 | ALDH1A1 (0.47) | MAPTSMN1; SMN2RECQLALDH1A1SLC6A5 | |
| SCHEMBL865338 | 0.84 | ALDH1A1 (0.47) | MAPTSMN1; SMN2RECQLALDH1A1SLC6A5 | |
| SCHEMBL12571476 | 0.84 | USP2 (0.48) | MAPTSMN1; SMN2RECQLALDH1A1USP2 | |
| SCHEMBL12513863 | 0.83 | MAPT (0.46) | MAPTSMN1; SMN2RECQLALDH1A1SLC6A5 | |
| SCHEMBL2894648 | 0.82 | SLC6A5 (0.59) | GNPATMAPTALDH1A1SLC6A5ABCC4 | |
| SCHEMBL2897531 | 0.82 | SLC6A5 (0.59) | GNPATMAPTALDH1A1SLC6A5ABCC4 | |
| SCHEMBL8148985 | 0.81 | USP2 (0.46) | MAPTSMN1; SMN2RECQLALDH1A1USP2 | |
| SCHEMBL13010934 | 0.81 | USP2 (0.46) | MAPTSMN1; SMN2RECQLALDH1A1USP2 | |
| SCHEMBL31370342 | 0.81 | MAPT (0.42) | GNPATMAPTSMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL17400530 | 0.81 | MAPT (0.47) | GNPATMAPTSMN1; SMN2RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115708891-A | Developing drug-loaded microsphere based on microfluidic technology and preparation method and application thereof | 四川大学 | 2023-02-24 | — | — | CN | disclosed |
| US-20100323953-A1 | MACROCYCLIC HEPATITIS C PROTEASE INHIBITORS | PHENOMIX CORPORATION (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2009102876-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20030181363-A1 | Macrocyclic peptides active against the hepatitis C virus | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323953-A1 | MACROCYCLIC HEPATITIS C PROTEASE INHIBITORS | CTSC, HAVCR2, TMPRSS15 | GNPAT 1558/4885MAPT 4213/4885SMN1; SMN2 4531/4885 |
| US-20030181363-A1 | Macrocyclic peptides active against the hepatitis C virus | CTRL, CPN1, CTRC | GNPAT 3733/4885MAPT 4716/4885SMN1; SMN2 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.