SCHEMBL3777976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3777108	0.90	ALDH1A1 (0.44)	TSHRPLA2G2APKMKDM4EALDH1A1
	SCHEMBL27826430	0.85	PLA2G2A (0.42)	PLA2G2APKMKDM4EALDH1A1HPGD
	SCHEMBL27743397	0.83	PLA2G2A (0.41)	PLA2G2APKMKDM4EALDH1A1HPGD
	SCHEMBL3776046	0.83	TDP1 (0.46)	TDP1TSHRPLA2G2APKMKDM4E
	SCHEMBL3780495	0.81	PTGDR2 (0.48)	PLA2G2AKDM4EPTGDR2KMT2A
	SCHEMBL3779792	0.81	ALDH1A1 (0.44)	TSHRPLA2G2APKMKDM4EALDH1A1
	SCHEMBL3779168	0.80	TDP1 (0.45)	TDP1TSHRTHRATHRBPTGDR2
	SCHEMBL3779606	0.79	PLA2G2A (0.37)	TDP1PLA2G2AKDM4EALDH1A1KMT2A
	SCHEMBL3788414	0.78	RORC (0.41)	TDP1PLA2G2AKDM4EALDH1A1HPGD
	SCHEMBL5329822	0.78	PKM (0.61)	TSHRPKMKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.