Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778947 | 0.90 | RAB9A (0.48) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL177614 | 0.78 | EPHX2 (0.52) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL2636923 | 0.77 | CA1 (0.37) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4490079 | 0.76 | MPO (0.53) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5885636 | 0.75 | LOXL2 (0.56) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5819828 | 0.75 | APP (0.49) | RAB9ANPC1LMNAEPHX2NR4A2 | |
| SCHEMBL6119612 | 0.73 | SRD5A2 (0.48) | ALDH1A1MAPTEPHX2NR4A2RXRA | |
| SCHEMBL7481751 | 0.73 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9546862 | 0.72 | MEN1 (0.65) | RAB9ANPC1MAPTLMNAPOLB | |
| SCHEMBL9402592 | 0.72 | MLYCD (0.42) | RAB9ANPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437792-B1 | IMAGING OF MYELIN BASIC PROTEIN | GEN ELECTRIC (US) | 2015-10-21 | — | — | EP | disclosed |
| US-8617515-B2 | Imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | RAB9A 1676/4885NPC1 1848/4885ALDH1A1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.