Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775369 | 0.87 | KCNK3 (0.64) | PTGESKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL3770483 | 0.87 | KMT2A (0.62) | PTGESNPC1RAB9AMTOR | |
| SCHEMBL3782416 | 0.86 | PTGES (0.66) | PTGESKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL3767063 | 0.86 | RHOC (0.63) | PTGESKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL3764441 | 0.85 | RAB9A (0.78) | KCNK3KCNK9NPC1RAB9AMTOR | |
| SCHEMBL3771572 | 0.84 | NPC1 (0.59) | PTGESNPC1RAB9ARXFP1MTOR | |
| SCHEMBL3771639 | 0.84 | NPC1 (0.75) | PTGESNPC1RAB9AF2RMTOR | |
| SCHEMBL3772942 | 0.84 | KCNK3 (0.62) | KCNK3KCNK9NPC1RAB9AMTOR | |
| SCHEMBL3771506 | 0.84 | NPC1 (0.75) | PTGESKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL3768814 | 0.83 | NPC1 (0.56) | PTGESKCNK3KCNK9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | PTGES 54/4885KCNK3 1692/4885KCNK9 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.