SCHEMBL378108

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL377924	0.85	SMN1; SMN2 (0.53)	MEN1KMT2AMAPTALDH1A1TSHR
	Hydrochloric Acid SCHEMBL2514818	0.85	MEN1 (0.50)	MEN1KMT2AHPGDHTTALDH1A1
	SCHEMBL381643	0.84	CKS1B (0.48)	MEN1KMT2AMAPTHPGDHTT
	SCHEMBL378276	0.82	TDP1 (0.60)	MEN1KMT2AMAPTHPGDHTT
	SCHEMBL20884874	0.82	RORC (0.54)	MEN1KMT2AMAPTHTTALDH1A1
	SCHEMBL3457437	0.82	HPGD (0.55)	MEN1KMT2AMAPTHPGDHTT
	SCHEMBL458122	0.82	ALDH1A1 (0.53)	MEN1KMT2AALDH1A1TSHRSMN1; SMN2
	SCHEMBL2384645	0.82	EPHX2 (0.51)	MEN1KMT2AMAPTHPGDALDH1A1
	SCHEMBL20188098	0.82	HPGD (0.65)	MEN1KMT2AMAPTHPGDHTT
	SCHEMBL22015905	0.82	HPGD (0.65)	MEN1KMT2AMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.