SCHEMBL9243675

SCHEMBL9243675

O=S(=O)(c1cc[c]cc1)c1ccc(Cl)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.73
CYP3A4 P08684 2/20 0.73
MAPK1 P28482 1/20 0.73
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
KDM4E B2RXH2 2/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA3 P07451 3/20 0.48
CA4 P22748 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA13 Q8N1Q1 3/20 0.48
CA14 Q9ULX7 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313173 0.85 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL818508 0.85 HTR6 (0.50) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 0.85 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328031 0.85 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2122579 0.85 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL16713293 0.83 ALDH1A1 (0.94) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL3781114 0.79 ALDH1A1 (0.42) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11590997 0.78 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5028733 0.78 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL7202895 0.78 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5446096-A Transparent polymer alloys; improved mechanical properties, workability ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1995-08-29 US disclosed
US-5378763-A Radiation transparent, melt processability, heat resistance ENICHEM S.P.A. (IT) 1995-01-03 US disclosed
US-4176222-A BY HEATING A BISPHENOL, DIHALOBENZENOID COMPOUND WITH SODIUM CARBONATE OR BICARBONATE AND A SECOND ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-11-27 US disclosed