Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 5/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649924 | 0.84 | LOXL2 (0.58) | DPP4HTR7LOXL2TAAR1CFD | |
| SCHEMBL3789280 | 0.84 | HTR7 (0.49) | DPP4HTR7LOXL2TAAR1CFD | |
| SCHEMBL14601394 | 0.83 | HTR7 (0.52) | DPP4HTR7LOXL2ADRA2CCFD | |
| SCHEMBL8986211 | 0.83 | HTR7 (0.60) | DPP4HTR7ADRA2CNOS3NOS1 | |
| SCHEMBL3789431 | 0.82 | DPP4 (0.72) | DPP4LOXL2TAAR1CSNK2A1PNMT | |
| SCHEMBL3787571 | 0.81 | DPP4 (0.64) | DPP4ADRA2CPNMTENPP2NOS3 | |
| SCHEMBL3790240 | 0.81 | ALDH1A1 (0.54) | DPP4HTR7LOXL2TAAR1CFD | |
| Formic Acid SCHEMBL28329379 | 0.81 | DPP4 (0.54) | DPP4HTR7ADRA2CCFDPLG | |
| SCHEMBL23329978 | 0.80 | HTR7 (0.42) | DPP4HTR7CFDF11TPSB2 | |
| SCHEMBL5478510 | 0.79 | DPP4 (0.62) | DPP4HTR7TAAR1ADRA2CPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | DPP4 3267/4885HTR7 1295/4885LOXL2 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.