Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788531 | 0.84 | HTR6 (0.38) | HTR6DPP4 | |
| SCHEMBL3786924 | 0.81 | HTR6 (0.50) | HTR6 | |
| SCHEMBL9378261 | 0.76 | DPP4 (0.36) | DPP4 | |
| SCHEMBL9015525 | 0.76 | NPSR1 (0.34) | DPP4 | |
| SCHEMBL9015560 | 0.74 | DPP4 (0.33) | DPP4 | |
| SCHEMBL9015546 | 0.74 | DPP4 (0.33) | DPP4 | |
| Cafenstrole SCHEMBL54625 | 0.74 | KMT2A (0.49) | DPP4 | |
| SCHEMBL9015559 | 0.73 | ALDH1A1 (0.39) | DPP4 | |
| SCHEMBL204666 | 0.73 | DPP4 (0.34) | DPP4 | |
| SCHEMBL3782113 | 0.72 | HTR6 (0.47) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552005-B2 | (EN) 3-sulfonyl-pyrazolo[1,5-a] pyrimidines / antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof | Avincuro Pharmaceuticals, Inc. (US) | 2013-10-08 | — | — | US | claimed |
| US-20100331347-A1 | (EN) 3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | AVINEURO PHARMACEUTICALS, INC. | 2010-12-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331347-A1 | (EN) 3-SULFONYL-PYRAZOLO[1,5-A] PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF | HTR6, HTR1A, HTR3A | HTR6 1/4885DPP4 2106/4885PTGS2 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.