SCHEMBL3783583

SCHEMBL3783583

[c]1cccc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.50
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
MPI P34949 1/20 0.42
HSD17B10 Q99714 3/20 0.40
HIF1A Q16665 2/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TRPM4 Q8TD43 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HPRT1 P00492 2/20 0.37
NISCH Q9Y2I1 1/20 0.37
GPR84 Q9NQS5 2/20 0.35
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20774190 0.82 HPRT1 (0.48) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL29232614 0.82 HSD17B1 (0.38) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL20773919 0.80 CYP1A2 (0.43) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL1368869 0.79 CA12 (0.41) ALDH1A1HPGDKDM4EMAPTHSD17B10
SCHEMBL1370360 0.79 ALOX5 (0.46) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL3783466 0.79 ALDH1A1 (0.45) CYP11B1ALDH1A1HPGDMAPTHSD17B10
SCHEMBL1371355 0.79 ALDH1A1 (0.35) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL1527435 0.79 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL9957971 0.78 MEN1 (0.46) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL9957834 0.78 CYP11B1 (0.42) CYP11B1ALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN claimed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO claimed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
CN-117801021-A Organometallic complex and light-emitting device 株式会社半导体能源研究所 2024-04-02 CN disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
CN-111094223-B binaphthyl compounds 罗伊特化学仪器制造公司 2023-10-27 CN disclosed
CN-111710788-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-07-21 CN disclosed
CN-110997633-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2023-07-04 CN disclosed
CN-111354874-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-07-04 CN disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-111341927-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-06-09 CN disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed
WO-2019043060-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU KG (DE) 2019-03-07 WO disclosed
CN-109311844-A Triaizine compounds, its manufacturing method and the organic electroluminescent device as constituent 东曹株式会社 2019-02-05 CN disclosed
CN-107778309-A A kind of and quinoline and its application 北京鼎材科技有限公司 2018-03-09 CN disclosed
CN-106573912-A Triazine compound, method for producing same, and application for same 东曹株式会社 2017-04-19 CN disclosed
US-8568903-B2 Phenanthrene derivative, and material for organic EL element IDEMITSU KOSAN CO., LTD. (JP) 2013-10-29 US disclosed
US-20100327230-A1 PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2010-12-30 US disclosed
US-20080287695-A1 Agent For Optical Resolution, Process For Producing Optically Active Substance and 1,5-Substituted Bicyclo [3.3.0] -2-Oxaoctane Compound ZEON CORPORATION (JP) 2008-11-20 US disclosed
EP-1719746-A1 OPTICAL RESOLVER, PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMER, AND 1,5-SUBSTITUTED BICYCLO (3.3.0) -2-OXAOCTANE COMPOUND ZEON CORPORATION (JP) 2006-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287695-A1 Agent For Optical Resolution, Process For Producing Optically Active Substance and 1,5-Substituted Bicyclo [3.3.0] -2-Oxaoctane Compound ALDH1A2, OXER1, HCRTR1 CYP11B1 657/4885ALDH1A1 26/4885MEN1 3108/4885
US-20100327230-A1 PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT LEF1, AR, NR0B1 CYP11B1 630/4885ALDH1A1 1250/4885MEN1 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.