Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL27774945 | 0.94 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL3790953 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL3787533 | 0.85 | TP53 (0.50) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL203121 | 0.83 | ADRB2 (0.61) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL3786128 | 0.82 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1TP53GLA | |
| Propane SCHEMBL27542299 | 0.81 | ADRB2 (0.59) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| Fluoride SCHEMBL27432507 | 0.81 | ADRB2 (0.59) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL3783523 | 0.81 | MAPK1 (0.53) | L3MBTL1MAPK1RAB9ATP53MAPT | |
| SCHEMBL7930788 | 0.80 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPK1TP53GLA | |
| SCHEMBL29290124 | 0.80 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524034-B | Preparation, pharmacological action and the application for treating cerebral ischemia of coumarin derivative | 北京大学 | 2018-08-17 | — | — | CN | disclosed |
| CN-103204813-A | Condensed imidazole derivatives as TRPV3 antagonist | GLENMARK PHARMACEUTICALS SA | 2013-07-17 | — | — | CN | disclosed |
| CN-103183659-A | Chromane derivative used as TRPV3 (transient receptor potential vanillin 3) regulator | GLENMARK PHARMACEUTICALS SA | 2013-07-03 | — | — | CN | disclosed |
| CN-103183660-A | Chromane derivative used as TRPV3 (transient receptor potential vanilloid 3) conditioning agent | GLENMARK PHARMACEUTICALS SA | 2013-07-03 | — | — | CN | disclosed |
| CN-102256969-A | Compounds that modulate intracellular calcium | CALCIMEDICA INC | 2011-11-23 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| CN-101687774-A | Benzamides useful as s1p receptor modulators | NOVARTIS AG | 2010-03-31 | — | — | CN | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-1910148-A | Indolylalanine derivatives as selective S1P4 agonists | NOVARTIS AG (CH) | 2007-02-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885ADORA3 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.