Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786163 | 0.92 | MAPT (0.53) | MAPK1MAPTL3MBTL1TDP1RXRA | |
| SCHEMBL3783759 | 0.89 | MAOB (0.54) | MAPK1MAPTL3MBTL1TDP1RXRA | |
| SCHEMBL11828242 | 0.85 | MAPT (0.64) | MAPK1MAPTL3MBTL1TDP1LTA4H | |
| SCHEMBL3785825 | 0.85 | L3MBTL1 (0.51) | MAPK1MAPTL3MBTL1TDP1LTA4H | |
| SCHEMBL201074 | 0.83 | RXRA (0.70) | MAPK1MAPTL3MBTL1TDP1RXRA | |
| SCHEMBL18075739 | 0.81 | MAPT (0.55) | MAPK1MAPTL3MBTL1TDP1RXRA | |
| SCHEMBL3784036 | 0.81 | ALDH1A1 (0.53) | MAPK1MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL6640539 | 0.81 | MAPT (0.55) | MAPK1MAPTL3MBTL1TDP1RXRA | |
| SCHEMBL3489533 | 0.80 | MAPT (0.58) | MAPK1MAPTL3MBTL1TDP1LTA4H | |
| SCHEMBL5109238 | 0.80 | PTGER1 (0.66) | MAPK1MAPTL3MBTL1TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MAPK1 4726/4885MAPT 3312/4885L3MBTL1 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.