Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803167 | 0.92 | ALDH1A1 (0.77) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL9342000 | 0.85 | ALDH1A1 (0.78) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL28401182 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1189632 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7916743 | 0.84 | ALDH1A1 (0.81) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL7250114 | 0.84 | ALDH1A1 (0.66) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL3788964 | 0.83 | ALDH1A1 (0.75) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL11402541 | 0.83 | GPR35 (1.00) | ALDH1A1GPR35HPGDSMN1; SMN2MAPT | |
| SCHEMBL6999775 | 0.81 | ALDH1A1 (0.71) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 | |
| SCHEMBL28455248 | 0.81 | ALDH1A1 (0.71) | ALDH1A1GPR35HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885GPR35 1486/4885HPGD 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.