Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146075 | 0.92 | MEN1 (0.60) | MEN1KMT2AMAPK1LMNAPDK1 | |
| SCHEMBL21681358 | 0.90 | LCK (0.46) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL23624071 | 0.89 | MEN1 (0.45) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL31605689 | 0.89 | MEN1 (0.45) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL21046968 | 0.89 | RXFP1 (0.43) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL24427984 | 0.89 | CXCR2 (0.48) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL29683229 | 0.89 | RXFP1 (0.43) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL6183442 | 0.88 | PDK1 (0.59) | GPR35MEN1KMT2AMAPK1RXFP1 | |
| SCHEMBL5802951 | 0.86 | LMNA (0.58) | MEN1KMT2AMAPK1RXFP1HSP90AA1 | |
| SCHEMBL22567756 | 0.85 | GPR35 (0.43) | GPR35MEN1KMT2AMAPK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | GPR35 1486/4885MEN1 174/4885KMT2A 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.