Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PPM1B | O75688 | 1/20 | 0.54 |
| ▸ | HNF4A | P41235 | 2/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575452 | 0.86 | PPM1B (0.71) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL30456877 | 0.86 | PPM1B (0.71) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL3781502 | 0.86 | IKBKB (0.55) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL3784526 | 0.85 | IKBKB (0.54) | IKBKBMEN1PPM1BMCL1MKNK2 | |
| SCHEMBL28033110 | 0.85 | PPM1B (0.54) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL3781950 | 0.85 | IKBKB (1.00) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL5332435 | 0.84 | IKBKB (0.72) | IKBKBHNF4AACMSDBCAT2SIRT2 | |
| SCHEMBL30595681 | 0.84 | IKBKB (0.72) | IKBKBHNF4AACMSDBCAT2SIRT2 | |
| SCHEMBL3789666 | 0.83 | IKBKB (0.56) | IKBKBKDM4EKMT2AMEN1USP2 | |
| SCHEMBL14392234 | 0.83 | IKBKB (0.56) | IKBKBKDM4EKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | IKBKB 2611/4885KDM4E 2606/4885KMT2A 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.