SCHEMBL7524261

SCHEMBL7524261

Nc1ccc(C(=O)c2ccc(N)cc2-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.55
RORB Q92753 1/20 0.55
PTGDR2 Q9Y5Y4 1/20 0.53
CYP3A4 P08684 5/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
ESR2 Q92731 1/20 0.46
PTPN1 P18031 1/20 0.46
BCAT2 O15382 1/20 0.46
PBRM1 Q86U86 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TP53 P04637 2/20 0.44
LMNA P02545 2/20 0.44
KDR P35968 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14744360 0.91 PBRM1 (0.53) RORCRORBPTGDR2MAPTALDH1A1
SCHEMBL31457340 0.90 MAPK13 (0.49) RORCRORBPTGDR2MAPTALDH1A1
SCHEMBL31377031 0.89 MAPT (0.55) RORCRORBPTGDR2CYP3A4MAPT
SCHEMBL451330 0.89 MAPT (0.55) RORCRORBPTGDR2CYP3A4MAPT
SCHEMBL3784596 0.87 BCAT2 (0.63) RORCRORBPTGDR2CYP3A4MAPT
Hydrochloric Acid SCHEMBL6775126 0.87 MAPT (0.53) RORCRORBPTGDR2CYP3A4MAPT
SCHEMBL7511520 0.86 RORC (0.51) RORCRORBPTGDR2CYP3A4MAPT
SCHEMBL3785938 0.85 PTGDR2 (0.50) RORCRORBPTGDR2CYP3A4MAPT
SCHEMBL630047 0.81 GAA (0.58) PTGDR2CYP3A4MAPTALDH1A1KDM4E
SCHEMBL29775249 0.81 GAA (0.58) PTGDR2CYP3A4MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0518571-B1 Favorably processable polyimide and process for preparing polyimide MITSUI CHEMICALS INC (JP) 2002-01-23 EP disclosed
US-5276133-A Heat resistant, dimensionaly stable polymers for molding materials used in electronics MITSUI TOATSU CHEMICALS, INC. (JP) 1994-01-04 US disclosed
EP-0518571-A2 Favorably processable polyimide and process for preparing polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-16 EP disclosed
US-4535105-A TETRACARBOXLYIC AROMATIC COMPOUND AND AROMATICDIAMINE UBE INDUSTRIES, LTD. (JP) 1985-08-13 US disclosed