Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790151 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HSD17B10RECQLL3MBTL1S100A4 | |
| SCHEMBL3783094 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HSD17B10L3MBTL1MAP2K7CDC25A | |
| SCHEMBL3787091 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10RECQLL3MBTL1S100A4 | |
| SCHEMBL3784048 | 0.81 | MAOA (0.45) | ALDH1A1HSD17B10EPHX2MEN1KMT2A | |
| SCHEMBL3783780 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HSD17B10L3MBTL1ADORA2AKDM4E | |
| SCHEMBL3789498 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10RECQLL3MBTL1S100A4 | |
| SCHEMBL3781383 | 0.76 | MAOA (0.48) | ALDH1A1RECQLEPHX2MEN1KDM4E | |
| SCHEMBL3790219 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10RECQLL3MBTL1S100A4 | |
| SCHEMBL3789535 | 0.75 | CYP3A4 (0.42) | ALDH1A1HSD17B10L3MBTL1EPHX2MEN1 | |
| SCHEMBL3803867 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10RECQLL3MBTL1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885HSD17B10 1100/4885RECQL 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.