Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784788 | 1.00 | MAPT (0.46) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL3794158 | 0.78 | PDE7A (0.46) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL3794156 | 0.78 | PDE7A (0.46) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL3787312 | 0.77 | VCAM1 (0.50) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL27317418 | 0.74 | VCAM1 (0.61) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL8153011 | 0.73 | MAPT (0.48) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL11799184 | 0.73 | MAPT (0.65) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL11799189 | 0.73 | MAPT (0.65) | MAPTMITFRECQLNPSR1RAB9A | |
| SCHEMBL535154 | 0.72 | ESR1 (0.38) | MAPTMITFNPSR1RAB9AALDH1A1 | |
| SCHEMBL25197868 | 0.71 | PAM (0.46) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947328-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-20200255552-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-10662264-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20180194877-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | BAYER HEALTHCARE LLC | 2018-07-12 | — | — | US | disclosed |
| US-9944725-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-20170044276-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | BAYER HEALTHCARE LLC | 2017-02-16 | — | — | US | disclosed |
| US-9505884-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2016-11-29 | — | — | US | disclosed |
| US-20160083519-A1 | Polymer Comprising A Plurality Of Phenothiazine Groups And Methods Of Making The Same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2016-03-24 | — | — | US | disclosed |
| US-9238717-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | BAYER HEALTHCARE LLC (US) | 2016-01-19 | — | — | US | disclosed |
| US-20140235797-A1 | Polymer Comprising A Plurality Of Phenothiazine Groups And Methods Of Making The Same | BAYER HEALTHCARE LLC (US) | 2014-08-21 | — | — | US | disclosed |
| US-8742063-B2 | Polymer bonded redox molecules and methods of making the same | BAYER HEALTHCARE LLC (US) | 2014-06-03 | — | — | US | disclosed |
| US-8283347-B2 | Redox molecules and methods of making the same | BAYER HEALTHCARE LLC (US) | 2012-10-09 | — | — | US | disclosed |
| US-20110294959-A1 | Polymer Bonded Redox Molecules And Methods Of Making The Same | BAYER HEALTHCARE LLC (US) | 2011-12-01 | — | — | US | disclosed |
| WO-2010141359-A2 | REDOX MOLECULES AND METHODS OF MAKING THE SAME | BAYER HEALTHCARE LLC (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100300896-A1 | Redox Molecules And Methods Of Making The Same | BAYER HEALTHCARE LLC (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100300896-A1 | Redox Molecules And Methods Of Making The Same | GPX4, GPX1, SOD1 | MAPT 4072/4885MITF 1055/4885RECQL 1374/4885 |
| US-20200255552-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
| US-20160083519-A1 | Polymer Comprising A Plurality Of Phenothiazine Groups And Methods Of Making The Same | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
| US-20180194877-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
| US-10947328-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
| US-20170044276-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
| US-10662264-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | PAH, TYK2, PNMT | MAPT 178/4885MITF 956/4885RECQL 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.