Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783624 | 0.86 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3781813 | 0.82 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3806744 | 0.79 | MAOA (0.48) | ALDH1A1HSD17B10ADORA2AKDM4EMAPT | |
| SCHEMBL3783514 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3790383 | 0.77 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3793122 | 0.76 | TSHR (0.48) | ALDH1A1KDM4EKDM1ASMN1; SMN2HPGD | |
| Diphenylsulfane SCHEMBL19712994 | 0.75 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3791406 | 0.75 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3780720 | 0.74 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E | |
| SCHEMBL3790087 | 0.74 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD17B10ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885HSD17B10 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.