Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orthotolidine SCHEMBL9650002 | 0.88 | CYP3A4 (0.55) | CYP3A4TSHRALDH1A1TDP1MAP4K4 | |
| Orthotolidine SCHEMBL49414 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| Orthotolidine SCHEMBL29365329 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| Orthotolidine SCHEMBL29386552 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1TDP1MEN1 | |
| SCHEMBL25261675 | 0.83 | ALDH1A1 (0.71) | CYP3A4TSHRALDH1A1TDP1MAP4K4 | |
| SCHEMBL3792051 | 0.83 | CASP1 (0.58) | CYP3A4TSHRALDH1A1TDP1MAP4K4 | |
| Hydrochloric Acid SCHEMBL1569886 | 0.83 | MAP4K4 (0.58) | CYP3A4TSHRALDH1A1TDP1MAP4K4 | |
| SCHEMBL29943184 | 0.83 | ALDH1A1 (0.71) | CYP3A4TSHRALDH1A1TDP1MAP4K4 | |
| SCHEMBL807858 | 0.83 | TDP1 (0.77) | CYP3A4TSHRALDH1A1TDP1MAOA | |
| Orthotolidine SCHEMBL20547383 | 0.82 | CYP3A4 (0.94) | CYP3A4TSHRALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885TSHR 1688/4885ALDH1A1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.