Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27188289 | 0.89 | ALDH1A1 (0.53) | SMN1; SMN2HDAC8PYGLPPARGHDAC6 | |
| SCHEMBL27188328 | 0.89 | PYGL (0.48) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 | |
| SCHEMBL10323952 | 0.87 | PLAU (0.50) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 | |
| SCHEMBL3783986 | 0.85 | PYGL (0.57) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 | |
| SCHEMBL4161973 | 0.84 | MEN1 (0.61) | HDAC8HDAC6HDAC2ALDH1A1HPGD | |
| SCHEMBL7987535 | 0.82 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL16521645 | 0.82 | HDAC8 (0.54) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 | |
| SCHEMBL11959873 | 0.81 | TAS1R3 (0.59) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 | |
| SCHEMBL12900908 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGALDH1A1HPGDKDM4E | |
| SCHEMBL27188293 | 0.81 | STAT3 (0.49) | SMN1; SMN2HDAC8PYGLHDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | SMN1; SMN2 4524/4885HDAC8 1421/4885PYGL 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.