Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781228 | 0.86 | DHODH (0.68) | DHODHCYP3A4TDP1MKNK1MKNK2 | |
| SCHEMBL24587538 | 0.83 | MKNK1 (0.55) | DHODHPARP10MKNK1MKNK2CA12 | |
| SCHEMBL3784634 | 0.82 | MAPT (0.47) | DHODHALDH1A1TP53CYP3A4TDP1 | |
| SCHEMBL3791008 | 0.81 | DHODH (0.57) | DHODHALDH1A1MKNK2CA12CA1 | |
| SCHEMBL3786517 | 0.81 | PARP10 (0.65) | PARP10ALDH1A1TP53CYP3A4TDP1 | |
| Benzidine SCHEMBL9460959 | 0.81 | PARP10 (0.65) | PARP10ALDH1A1TP53CYP3A4TDP1 | |
| SCHEMBL3165972 | 0.78 | ERN1 (0.57) | DHODHERN1 | |
| SCHEMBL21253164 | 0.78 | ATAD2 (0.50) | PARP10ALDH1A1MKNK1MKNK2CA12 | |
| SCHEMBL890399 | 0.78 | CYP3A4 (0.44) | DHODHPARP10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL1807992 | 0.78 | KDM4E (0.46) | DHODHPARP10ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | DHODH 869/4885PARP10 1861/4885ALDH1A1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.