Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911616 | 0.87 | HDAC2 (0.71) | HDAC2HDAC8HDAC6HDAC1PTPN1 | |
| SCHEMBL1933481 | 0.86 | HDAC1 (0.63) | TRPV1HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL25160333 | 0.85 | F2 (0.49) | TRPV1PTPN1NPC1RAB9AHTT | |
| SCHEMBL29951893 | 0.84 | ALOX5 (0.76) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL387376 | 0.84 | TRPV1 (0.81) | TRPV1HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL3783926 | 0.82 | KCNK3 (0.65) | TRPV1PTPN1KCNK3KCNK9SIRT1 | |
| SCHEMBL177468 | 0.80 | TRPV1 (0.81) | TRPV1PTPN1SIRT1NPC1RAB9A | |
| SCHEMBL3789938 | 0.79 | KCNK3 (0.71) | TRPV1KCNK3KCNK9SIRT1NPC1 | |
| SCHEMBL14715899 | 0.79 | PTPN1 (0.77) | HDAC2HDAC8HDAC6HDAC1PTPN1 | |
| SCHEMBL8374911 | 0.79 | HDAC1 (0.85) | HDAC2HDAC8HDAC6HDAC1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TRPV1 1353/4885HDAC2 549/4885HDAC8 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.