SCHEMBL3787371

SCHEMBL3787371

C=C(CCOc1ccc(Br)c(Br)c1Br)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 11/20 0.35
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
USP2 O75604 1/20 0.34
HTR1B P28222 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150208 0.92 TDP1 (0.38) TDP1KDM4ELMNASMN1; SMN2MEN1
SCHEMBL7524447 0.80 HTR1B (0.53) TDP1KDM4ELMNASMN1; SMN2MEN1
SCHEMBL7520478 0.79 KDM4E (0.54) KDM4ELMNASMN1; SMN2MEN1KMT2A
SCHEMBL148282 0.77 TDP1 (0.39) TDP1KDM4ELMNASMN1; SMN2MEN1
SCHEMBL94045 0.75 TDP1 (0.37) TDP1KDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL10706913 0.74 THRA (0.37) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL10457118 0.73 F2 (0.43) TDP1KDM4ELMNASMN1; SMN2MEN1
SCHEMBL11406541 0.73 F2 (0.39) TDP1KDM4ELMNASMN1; SMN2MEN1
SCHEMBL5282277 0.73 KDM4E (0.30) KDM4EMEN1KMT2AALDH1A1CYP1A2
SCHEMBL5704184 0.73 THRB (0.42) TDP1KDM4ELMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807015-B1 PREVENTION OF GROOVE TIP DEFORMATION IN BRIGHTNESS ENHANCEMENT FILM MINNESOTA MINING & MFG (US) 1999-08-25 EP claimed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP claimed
EP-2519472-B1 ZIRCONIA-BASED PARTICLES DOPED WITH A LANTHANIDE ELEMENT 3M INNOVATIVE PROPERTIES CO (US) 2018-07-25 EP disclosed
US-9950932-B2 Zirconia-based particles doped with a lanthanide element 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-04-24 US disclosed
EP-1836128-B1 ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2017-10-11 EP disclosed
US-20130222738-A1 COLOR LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2013-08-29 US disclosed
US-20120264588-A1 ZIRCONIA-BASED PARTICLES DOPED WITH A LANTHANIDE ELEMENT 3M INNOVATIVE PROPERTIES COMPANY 2012-10-18 US disclosed
US-7674523-B2 hydrothermal treatment 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-03-09 US disclosed
US-20080305943-A1 ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2008-12-11 US disclosed
US-7429422-B2 Zirconia particles 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-09-30 US disclosed
US-20070232705-A1 ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-10-04 US disclosed
EP-1836128-A1 ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-26 EP disclosed
US-7241437-B2 Zirconia particles 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-10 US disclosed
WO-2006073783-A1 ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-13 WO disclosed
US-20060148950-A1 Zirconia particles 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US disclosed
EP-0246084-B1 PROCESS FOR PRINTING PREDETERMINED PATTERNS OM POLY (M-PHENYLENE- ISOPTHALAMIDE)TEXTILE FABRIC AND STABLE, HOMOGENEOUS PRINT PASTE THEREFOR Burlington Industries, Inc. (US) 1992-07-15 EP disclosed
EP-0246084-A2 Process for printing predetermined patterns om poly (m-phenylene- isopthalamide)textile fabric and stable, homogeneous print paste therefor Burlington Industries, Inc. (US) 1987-11-19 EP disclosed
US-4705523-A Process for improving the flame-retardant properties of printed shaped articles from aramid fibers BURLINGTON INDUSTRIES, INC. (US) 1987-11-10 US disclosed