SCHEMBL5282277

SCHEMBL5282277

C=C(CCOc1c(Br)c(Br)c(Br)c(Br)c1Br)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586401 0.88 PTPN1 (0.42) KDM4EMEN1ALDH1A1CYP1A2CYP2D6
SCHEMBL5586405 0.79 THRB (0.42) KDM4EMEN1ALDH1A1CYP1A2CYP2D6
SCHEMBL10706913 0.79 THRA (0.37) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL10405985 0.73 ALDH1A1 (0.44) KDM4EMEN1ALDH1A1CYP1A2CYP2D6
SCHEMBL3787371 0.73 TDP1 (0.36) KDM4EMEN1ALDH1A1CYP1A2CYP2D6
SCHEMBL8997216 0.72 THRA (0.44)
SCHEMBL2360332 0.72 RXRA (0.33) ALDH1A1CYP1A2
SCHEMBL3873305 0.72 L3MBTL1 (0.53) ALDH1A1CYP1A2
SCHEMBL6901218 0.72 KDM4E (0.46) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL7520478 0.70 KDM4E (0.54) KDM4EMEN1ALDH1A1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007007332-A1 TRIBROMONEOPENTYL (METH)ACRYLATE BASED COPOLYMERS AND LENSES MADE THEREFROM H.P.O.P - HIGH PERFORMANCE OPTICAL POLYMERS LTD. (IL) 2007-01-18 WO disclosed