Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018079 | 0.89 | TSHR (0.53) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3784574 | 0.85 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22927643 | 0.83 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AHPGDPDK1 | |
| SCHEMBL9653150 | 0.82 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL355700 | 0.81 | HSP90AA1 (0.67) | ALDH1A1HPGDSMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL12599208 | 0.81 | NPC1 (0.49) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10213485 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL30451635 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL20060875 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL1020385 | 0.81 | AURKA (0.43) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885NPC1 724/4885RAB9A 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.