SCHEMBL37877

SCHEMBL37877

OCCc1cccc(F)c1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.63
TDP1 Q9NUW8 1/20 0.52
SLC6A3 Q01959 2/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
DAO P14920 2/20 0.49
DRD2 P14416 1/20 0.49
SLC6A4 P31645 1/20 0.49
CYP4F2 P78329 2/20 0.47
CYP4A11 Q02928 2/20 0.47
MIF P14174 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6988122 0.87 TAAR1 (0.54) TAAR1SLC6A3DAOCYP4F2CYP4A11
SCHEMBL81108 0.87 TAAR1 (0.59) TAAR1SLC6A3IDO1AGXTDAO
SCHEMBL3371633 0.85 TAAR1 (0.74) TAAR1SLC6A3IDO1AGXTDAO
SCHEMBL1043921 0.85 TAAR1 (0.57) TAAR1SLC6A3IDO1AGXTDAO
SCHEMBL1047220 0.84 TAAR1 (0.55) TAAR1SLC6A3DRD2SLC6A4CYP4F2
SCHEMBL2955082 0.84 TAAR1 (0.55) TAAR1SLC6A3DRD2SLC6A4CYP4F2
SCHEMBL239199 0.83 TDP1 (0.65) TAAR1TDP1DRD2CYP4F2CYP4A11
SCHEMBL38187 0.81
SCHEMBL30583036 0.81
SCHEMBL15736377 0.81 TAAR1 (0.57) TAAR1SLC6A3IDO1AGXTDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020064917-A1 PRODUCTION OF AMINES VIA A HYDROAMINOMETHYLATION REACTION USING IMINIUM REACTANTS Universität Wien (AT) 2020-04-02 WO claimed
EP-3628657-A1 PRODUCTION OF AMINES VIA A HYDROAMINOMETHYLATION REACTION USING IMINIUM REACTANTS Universität Wien (AT) 2020-04-01 EP claimed
WO-2015172747-A1 SPIROCYCLIC MOLECULES AS MTH1 INHIBITORS WANG ZHAOYIN (CN) 2015-11-19 WO claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 US disclosed
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2025-04-17 US disclosed
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2025-03-27 US disclosed
CN-119528906-A Azaspiro compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2025-02-28 CN disclosed
WO-2025014719-A2 TROPANE COMPOUNDS FOR TREATING BRAIN DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-16 WO disclosed
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2024-12-12 US disclosed
EP-0251775-B1 ALPHA-ARYL-ALPHA-PHENYLETHYL-1H-1,2,4-TRIAZOLE-1-PROPANENITRILES ROHM AND HAAS COMPANY (US) 1993-01-20 EP disclosed
CN-1068118-A Imidazo [2, 1-b ] [3] benzazepine derivatives, compositions and methods of use JANSSEN PHARMACEUTICA NV (BE) 1993-01-20 CN disclosed
WO-1992022551-A1 IMIDAZO[2,1-b][3]BENZAZEPINE DERIVATIVES, COMPOSITIONS AND METHOD OF USE JANSSEN PHARMACEUTICA N.V. (BE) 1992-12-23 WO disclosed
EP-0518435-A1 Imidazo[2,1-b][3]benzazepine derivatives, compositions and method of use JANSSEN PHARMACEUTICA N.V. (BE) 1992-12-16 EP disclosed
EP-0496342-A1 New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient Nippon Kayaku Kabushiki Kaisha (JP) 1992-07-29 EP disclosed
US-5087635-A Funcicides ROHM AND HAAS COMPANY (US) 1992-02-11 US disclosed
EP-0380312-A1 Pesticidal compounds ROUSSEL-UCLAF (FR) 1990-08-01 EP disclosed
EP-0251775-A2 Alpha-aryl-alpha-phenylethyl-1H-1,2,4-triazole-1-propanenitriles ROHM AND HAAS COMPANY (US) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS ERG28, DPM1, CYP51A1 TAAR1 3783/4885TDP1 3324/4885SLC6A3 4336/4885
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885TDP1 863/4885SLC6A3 89/4885
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF ADH1C, HTR6, CNR1 TAAR1 97/4885TDP1 387/4885SLC6A3 43/4885
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 TAAR1 2815/4885TDP1 2489/4885SLC6A3 3310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.