Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3787736 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9950133 | 1.00 | — | — | |
| Bicarbonate SCHEMBL14562563 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL1315914 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5189028 | 0.94 | — | — | |
| Bicarbonate SCHEMBL22798641 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5189025 | 0.94 | — | — | |
| Bicarbonate SCHEMBL22799023 | 0.94 | — | — | |
| Bicarbonate SCHEMBL22798890 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8376231 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200147581-A1 | METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2020-05-14 | — | — | US | claimed |
| US-20190345122-A1 | METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2019-11-14 | — | — | US | claimed |
| CN-110179835-A | Improve the composition of human skin health and its prepares the purposes in product | 美国宝微技术股份有限公司 | 2019-08-30 | — | — | CN | claimed |
| WO-2019152524-A1 | METHODS FOR STABILIZING BACTERIAL PROBIOTIC COMPOSITIONS | BiOWiSH Technologies, Inc. (US) | 2019-08-08 | — | — | WO | claimed |
| US-20190231882-A1 | METHODS FOR STABILIZING BACTERIAL PROBIOTIC COMPOSITIONS | BIOWISH TECHNOLOGIES, INC., ASSIGNOR | 2019-08-01 | — | — | US | claimed |
| CN-106794202-B | Composition for improving human skin health and use thereof in preparing products | 百通生物技术公司 | 2019-06-21 | — | — | CN | claimed |
| US-20170271637-A1 | METHOD OF MANUFACTURING POROUS POLYMER MEMBRANE USING WATER PRESSURE AND BATTERY SEPARATOR COMPRISING POROUS POLYMER MEMBRANE MANUFACTURED BY THE METHOD | SANGMYUNG UNIVERSITY SEOUL INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2017-09-21 | — | — | US | claimed |
| US-9717767-B2 | Compositions and methods for improving human health and nutrition | BiOWiSH Technologies, Inc. (US) | 2017-08-01 | — | — | US | claimed |
| CN-106794202-A | Compositions and methods for improving human health and nutrition | 百通生物技术公司 | 2017-05-31 | — | — | CN | claimed |
| WO-2015175536-A1 | COMPOSITIONS AND METHODS FOR IMPROVING HUMAN HEALTH AND NUTRITION | BiOWiSH Technologies, Inc. (US) | 2015-11-19 | — | — | WO | claimed |
| US-20150320809-A1 | COMPOSITIONS AND METHODS FOR IMPROVING HUMAN HEALTH AND NUTRITION | BIOWISH TECHNOLOGIES, INC., ASSIGNOR | 2015-11-12 | — | — | US | claimed |
| WO-2007140525-A1 | A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION | HOENIG MICHEL (AU) | 2007-12-13 | — | — | WO | claimed |
| US-20260125603-A1 | ISOMERIZATION OF BIOFEEDS OVER BASE METAL CATALYSTS | EXXONMOBIL TECHNOLOGY AND ENGINEERING CO (US) | 2026-05-07 | — | — | US | disclosed |
| US-12503655-B2 | Isomerization of biofeeds over base metal catalysts | ExxonMobil Technology and Engineering Company (US) | 2025-12-23 | — | — | US | disclosed |
| US-12503654-B2 | Reduced H2 consumption during deoxygenation | ExxonMobil Technology and Engineering Company (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4642870-A1 | BASE METAL ISOMERIZATION CATALYSTS | ExxonMobil Technology and Engineering Company (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20030065113-A1 | Transition metal catalysts for olefin polymerization | EQUISTAR CHEMICALS, LP | 2003-04-03 | — | — | US | disclosed |
| US-6383975-B1 | CATALYTIC HYDROTREATMENT OF MIDDLE AND HEAVY OILS, IMPREGNATION OF GROUP IVB METAL ON ALUMINA, DRYING AND ROASTING IMPREGNATION OF THE ALUMINA WITH A TI COMPOUND, SOLUBLE IN AN ORGANIC SOLVENT, | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2002-05-07 | — | — | US | disclosed |
| US-5167876-A | Protective clothing; military aircraft interiors | ALLIED-SIGNAL INC. (US) | 1992-12-01 | — | — | US | disclosed |
| WO-1992010363-A1 | FLAME RESISTANT BALLISTIC COMPOSITE | ALLIED-SIGNAL INC. (US) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125603-A1 | ISOMERIZATION OF BIOFEEDS OVER BASE METAL CATALYSTS | CYP4F8, SLC6A12, DBF4 | CA1 109/4885CA2 56/4885CA9 507/4885 |
| US-20190345122-A1 | METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS | TYR, CRY2, CRY1 | CA1 356/4885CA2 31/4885CA9 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.