Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320384 | 0.90 | TAAR1 (0.64) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL1100010 | 0.87 | MAP4K4 (0.48) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL31432876 | 0.84 | MAOA (0.54) | TAAR1CYP3A4TDP1ALDH1A1MAP4K4 | |
| SCHEMBL3785980 | 0.84 | MAOA (0.54) | TAAR1CYP3A4TDP1ALDH1A1MAP4K4 | |
| SCHEMBL3644396 | 0.82 | CYP3A4 (0.69) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL16910639 | 0.82 | CYP3A4 (0.69) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL20615544 | 0.80 | TAAR1 (0.46) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL3785263 | 0.77 | MAOA (0.58) | TAAR1CYP3A4MAP4K4BRD4MEN1 | |
| SCHEMBL23910015 | 0.77 | KIF11 (0.61) | TAAR1CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL125516 | 0.76 | ALDH1A1 (0.69) | TAAR1CYP3A4TDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TAAR1 1746/4885CYP3A4 177/4885TDP1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.