Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784887 | 0.85 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8107404 | 0.84 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3790082 | 0.82 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3783663 | 0.79 | MAOA (0.42) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6011318 | 0.78 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3791666 | 0.76 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6572508 | 0.75 | HTR6 (0.33) | ALDH1A1SMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL3786718 | 0.75 | CYP3A4 (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL3789437 | 0.75 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3790124 | 0.74 | MAP4K4 (0.49) | CYP3A4TSHRMEN1TDP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885SMN1; SMN2 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.