Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CEL | P19835 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790008 | 0.98 | TSHR (0.46) | PTGDR2PTGDRPTGER2TSHRCYP3A4 | |
| SCHEMBL3781247 | 0.94 | NOS3 (0.47) | PTGDR2PTGDRPTGER2TSHRCYP3A4 | |
| SCHEMBL3791534 | 0.90 | TSHR (0.50) | PTGDR2PTGDRPTGER2TSHRCYP3A4 | |
| SCHEMBL3787194 | 0.85 | TSHR (0.45) | PTGDR2PTGDRPTGER2TSHRCYP3A4 | |
| SCHEMBL3791180 | 0.82 | TSHR (0.46) | PTGDR2PTGDRPTGER2TSHRCYP3A4 | |
| SCHEMBL3795015 | 0.82 | CHRNB2 (0.55) | PTGDR2PTGDRPTGER2TSHRSMN1; SMN2 | |
| SCHEMBL5150614 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TDP1KDM4ECEL | |
| SCHEMBL29974719 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TDP1KDM4ECEL | |
| SCHEMBL126782 | 0.80 | PTGDR2 (0.50) | PTGDR2PTGDRPTGER2TSHRGCGR | |
| SCHEMBL3793544 | 0.79 | CHRNB2 (0.57) | PTGDR2PTGDRPTGER2TSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | PTGDR2 3672/4885PTGDR 3717/4885PTGER2 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.