SCHEMBL3790990

SCHEMBL3790990

CN(C)CCNc1cccc2c1C(=O)c1c(O)ccc(NCCN(C)C)c1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.53
▸ SMN1; SMN2 Q16637 4/20 0.52
▸ HIF1A Q16665 2/20 0.52
▸ BRCA1 P38398 1/20 0.52
▸ NQO1 P15559 1/20 0.52
▸ CYP19A1 P11511 1/20 0.51
▸ MEN1 O00255 4/20 0.49
▸ BLM P54132 4/20 0.49
▸ KMT2A Q03164 4/20 0.49
▸ LMNA P02545 3/20 0.49
▸ MAPK1 P28482 3/20 0.49
▸ RECQL P46063 3/20 0.49
▸ EGFR P00533 3/20 0.49
▸ POLB P06746 3/20 0.49
▸ HTT P42858 2/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ MAPT P10636 2/20 0.49
▸ NPSR1 Q6W5P4 2/20 0.49
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ RAD52 P43351 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086164 0.97 TERT (0.56) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL29852887 0.97 TERT (0.56) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL15957181 0.95 SMN1; SMN2 (0.52) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL15691061 0.94 TERT (0.48) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL31218592 0.91 SMN1; SMN2 (0.62) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL13464403 0.90 NQO1 (0.48) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL17732421 0.90 SMN1; SMN2 (0.49) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL11277491 0.89 CYP19A1 (0.62) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL3418071 0.89 CYP19A1 (0.62) TERTSMN1; SMN2HIF1ABRCA1NQO1
SCHEMBL11522777 0.89 CYP19A1 (0.62) TERTSMN1; SMN2HIF1ABRCA1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NUMA1 TERT 2763/4885SMN1; SMN2 2265/4885HIF1A 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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