Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | METAP2 | P50579 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.61 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987531 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL3791414 | 0.87 | SMO (0.61) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL437231 | 0.87 | ALDH1A1 (0.87) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL6841680 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11266259 | 0.85 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11266257 | 0.85 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL3790280 | 0.84 | HPGD (0.56) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7067826 | 0.83 | MEN1 (0.71) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7183238 | 0.82 | RAB9A (0.67) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL3478178 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |