Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429345 | 0.81 | HTR6 (0.30) | — | |
| SCHEMBL29357487 | 0.78 | IDO1 (0.57) | IDO1SIGMAR1ADRA2AADRA1ALMNA | |
| SCHEMBL145977 | 0.78 | IDO1 (0.57) | IDO1SIGMAR1ADRA2AADRA1ALMNA | |
| SCHEMBL9428713 | 0.77 | CREBBP (0.40) | LMNAALDH1A1 | |
| SCHEMBL15875427 | 0.76 | MT-CO2 (0.40) | ALDH1A1 | |
| SCHEMBL6784204 | 0.75 | IDO1 (0.53) | IDO1SIGMAR1 | |
| SCHEMBL18440245 | 0.73 | SIGMAR1 (0.54) | IDO1SIGMAR1LMNA | |
| SCHEMBL5698322 | 0.72 | HTR2A (0.44) | SIGMAR1ADRA1ALMNACYP2D6ALDH1A1 | |
| SCHEMBL7185802 | 0.72 | HTR2A (0.35) | IDO1CYP2D6 | |
| SCHEMBL6542312 | 0.72 | SIGMAR1 (0.56) | IDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11628145-B2 | Coloured keratolytic nail lacquer | OYSTERSHELL NV (BE) | 2023-04-18 | — | — | US | disclosed |
| EP-3366277-B1 | PEELABLE NAIL LACQUER | OYSTERSHELL NV (BE) | 2021-11-17 | — | — | EP | disclosed |
| US-11147774-B2 | Peelable nail lacquer | OYSTERSHELL NV (BE) | 2021-10-19 | — | — | US | disclosed |
| US-10987376-B2 | Methods of treating and/or preventing nail disorders and/or improving the appearance of a nail | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2021-04-27 | — | — | US | disclosed |
| EP-3585358-B1 | COLOURED KERATOLYTIC NAIL LACQUER | OYSTERSHELL NV (BE) | 2020-12-16 | — | — | EP | disclosed |
| EP-3585357-B1 | PEELABLE NAIL LACQUER | OYSTERSHELL NV (BE) | 2020-12-09 | — | — | EP | disclosed |
| US-20200230088-A1 | COLOURED KERATOLYTIC NAIL LACQUER | OYSTERSHELL NV (BE) | 2020-07-23 | — | — | US | disclosed |
| US-20200030249-A1 | PEELABLE NAIL LACQUER | OYSTERSHELL NV (BE) | 2020-01-30 | — | — | US | disclosed |
| WO-2018154086-A1 | COLOURED KERATOLYTIC NAIL LACQUER | OYSTERSHELL NV (BE) | 2018-08-30 | — | — | WO | disclosed |
| WO-2018154085-A1 | PEELABLE NAIL LACQUER | OYSTERSHELL NV (BE) | 2018-08-30 | — | — | WO | disclosed |
| US-20160095811-A1 | METHODS OF TREATING AND/OR PREVENTING NAIL DISORDERS AND/OR IMPROVING THE APPEARANCE OF A NAIL | NAIL GENESIS LLC | 2016-04-07 | — | — | US | disclosed |
| EP-2996774-A1 | METHODS OF TREATING AND/OR PREVENTING NAIL DISORDERS AND/OR IMPROVING THE APPEARANCE OF A NAIL | Chesson Laboratory Associates, Inc. (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9259436-B2 | Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2016-02-16 | — | — | US | disclosed |
| WO-2014186355-A1 | METHODS OF TREATING AND/OR PREVENTING NAIL DISORDERS AND/OR IMPROVING THE APPEARANCE OF A NAIL | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2014-11-20 | — | — | WO | disclosed |
| EP-2207535-B1 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | CHESSON LAB ASSOCIATES INC (US) | 2014-08-27 | — | — | EP | disclosed |
| US-20140212370-A1 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8771725-B2 | Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2207535-A2 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | Chesson Laboratory Associates, Inc. (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009051648-A2 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | CHESSON LABORATORY ASSOCIATES, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090098194-A1 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | EPI HEALTH, LLC | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212370-A1 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | PUF60, UROD, UNG | IDO1 1885/4885SIGMAR1 2489/4885GID4 3960/4885 |
| US-10987376-B2 | Methods of treating and/or preventing nail disorders and/or improving the appearance of a nail | POLR1C, NACA, PIK3C3 | IDO1 327/4885SIGMAR1 2646/4885GID4 3432/4885 |
| US-20160095811-A1 | METHODS OF TREATING AND/OR PREVENTING NAIL DISORDERS AND/OR IMPROVING THE APPEARANCE OF A NAIL | POLR1C, NACA, PIK3C3 | IDO1 327/4885SIGMAR1 2646/4885GID4 3432/4885 |
| US-20090098194-A1 | POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME | PUF60, UROD, UNG | IDO1 1885/4885SIGMAR1 2489/4885GID4 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.