SCHEMBL379352

SCHEMBL379352

CCN(CC)CCCCC([SiH3])(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.40
ALDH1A1 P00352 1/20 0.35
USP2 O75604 1/20 0.31
CHRM2 P08172 1/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379298 0.94 SIGMAR1 (0.33) SIGMAR1ALDH1A1USP2APOBEC3AAPOBEC3G
SCHEMBL379784 0.85 MEN1 (0.30)
SCHEMBL380329 0.82 SIGMAR1 (0.42) SIGMAR1ALDH1A1APOBEC3AAPOBEC3G
SCHEMBL7898954 0.80 PAOX (0.36) USP2CHRM2
SCHEMBL380031 0.78 ALDH1A1 (0.43) SIGMAR1ALDH1A1
SCHEMBL379492 0.75 SIGMAR1 (0.36) SIGMAR1APOBEC3AAPOBEC3G
SCHEMBL23748415 0.73 TSHR (0.40)
SCHEMBL12805505 0.73 TSHR (0.40)
SCHEMBL4232263 0.73 TSHR (0.40)
SCHEMBL6047731 0.73 TSHR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511334-B1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2018-04-25 EP disclosed
EP-2174801-B1 Rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2016-10-19 EP disclosed
US-8800621-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-12 US disclosed
US-20120283354-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-08 US disclosed
EP-2366558-B1 Tire rubber composition and heavy-load tire SUMITOMO RUBBER IND (JP) 2012-10-31 EP disclosed
EP-2511334-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2012-10-17 EP disclosed
EP-2366557-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-05-23 EP disclosed
US-8163821-B2 Tire rubber composition and heavy-load tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-24 US disclosed
EP-2184317-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-04-18 EP disclosed
US-8119721-B2 Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-02-21 US disclosed
US-20110230613-A1 TIRE RUBBER COMPOSITION AND HEAVY-LOAD TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
US-20110230593-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
EP-2366557-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2366558-A1 Tire rubber composition and heavy-load tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed