Thioinosine Monophosphate

Thioinosine Monophosphate

SCHEMBL379365

O=P(O)(O)OC[C@H]1O[C@@H](n2cnc3c(S)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 11/20 0.77
P2RY1 P47900 4/20 0.77
TAS1R3 Q7RTX0 3/20 0.77
TAS1R1 Q7RTX1 3/20 0.77
P2RY2 P41231 3/20 0.77
SRC P12931 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
PRKAB2 O43741 1/20 0.77
TRPM2 O94759 1/20 0.77
LDHA P00338 1/20 0.77
ADRB2 P07550 1/20 0.77
FBP1 P09467 1/20 0.77
ADORA1 P30542 1/20 0.77
PRKAG1 P54619 1/20 0.77
PRKAA2 P54646 1/20 0.77
PDE4D Q08499 1/20 0.77
KCNH2 Q12809 1/20 0.77
PRKAA1 Q13131 1/20 0.77
PDE3A Q14432 1/20 0.77
P2RY11 Q96G91 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioinosine Monophosphate SCHEMBL29746215 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL15810629 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL379366 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL8711009 0.96 DNPH1 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1905818 0.92 P2RX3 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1905822 0.92 P2RX3 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1906288 0.91 P2RY1 (0.74) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1906291 0.91 P2RY1 (0.74) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL6368891 0.91 ADORA1 (0.68) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL3859612 0.90 P2RY1 (0.67) DNPH1P2RY1TAS1R3TAS1R1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295671-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2025-09-25 US claimed
US-12357642-B2 Hazardous agent injection system ANTARES PHARMA, INC. (US) 2025-07-15 US claimed
EP-4427737-A2 HAZARDOUS AGENT INJECTION SYSTEM Antares Pharma, Inc. (US) 2024-09-11 EP claimed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN claimed
US-20230104341-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2023-04-06 US claimed
US-11497753-B2 Hazardous agent injection system ANTARES PHARMA, INC. (US) 2022-11-15 US claimed
US-20200163975-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2020-05-28 US claimed
US-20170361021-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2017-12-21 US claimed
US-20170043093-A1 Hazardous Agent Injection System ASSERTIO SPECIALTY PHARMACEUTICALS, LLC 2017-02-16 US claimed
WO-2016027106-A1 CELL ASSAY UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2016-02-25 WO claimed
US-20150119799-A1 Hazardous Agent Injection System ASSERTIO SPECIALTY PHARMACEUTICALS, LLC 2015-04-30 US claimed
WO-2014165136-A1 CONSTANT VOLUME PREFILLED SYRINGES AND KITS THEREOF ANTARES PHARMA, INC. (US) 2014-10-09 WO claimed
EP-2408493-A1 HAZARDOUS AGENT INJECTION SYSTEM Antares Pharma, Inc. (US) 2012-01-25 EP claimed
WO-2010108116-A1 HAZARDOUS AGENT INJECTION SYSTEM ANTARES PHARMA, INC. (US) 2010-09-23 WO claimed
US-7727737-B2 Kit for rapid determination of thiopurine methyltransferase activity MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2010-06-01 US claimed
EP-0554363-B1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1998-06-24 EP claimed
US-4826824-A Method of enhancing the taste perception of sweetness of aspartame and derivatives thereof DUKE UNIVERSITY (US) 1989-05-02 US claimed
US-12629483-B2 Syringe shock absorber for use in an injection device ANTARES PHARMA, INC. (US) 2026-05-19 US disclosed
US-5095007-A Enzyme inhibitors GILLETTE COMPANY, THE 1992-03-10 US disclosed
US-4826824-A Method of enhancing the taste perception of sweetness of aspartame and derivatives thereof DUKE UNIVERSITY (US) 1989-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170043093-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20230104341-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20150119799-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-11497753-B2 Hazardous agent injection system TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20250295671-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20170361021-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-12629483-B2 Syringe shock absorber for use in an injection device SLC6A4, SSTR4, SLC6A2 DNPH1 3130/4885P2RY1 486/4885TAS1R3 3035/4885
US-20200163975-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-12357642-B2 Hazardous agent injection system TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.