Thioinosine Monophosphate

Thioinosine Monophosphate

SCHEMBL379366

O=P(O)(O)OC[C@H]1O[C@@H](n2cnc3c(S)ncnc32)C(O)C1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 11/20 0.77
P2RY1 P47900 4/20 0.77
TAS1R3 Q7RTX0 3/20 0.77
TAS1R1 Q7RTX1 3/20 0.77
P2RY2 P41231 3/20 0.77
SRC P12931 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
PRKAB2 O43741 1/20 0.77
TRPM2 O94759 1/20 0.77
LDHA P00338 1/20 0.77
ADRB2 P07550 1/20 0.77
FBP1 P09467 1/20 0.77
ADORA1 P30542 1/20 0.77
PRKAG1 P54619 1/20 0.77
PRKAA2 P54646 1/20 0.77
PDE4D Q08499 1/20 0.77
KCNH2 Q12809 1/20 0.77
PRKAA1 Q13131 1/20 0.77
PDE3A Q14432 1/20 0.77
P2RY11 Q96G91 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioinosine Monophosphate SCHEMBL29746215 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL15810629 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL379365 1.00 DNPH1 (0.77) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL8711009 0.96 DNPH1 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1905818 0.92 P2RX3 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1905822 0.92 P2RX3 (0.72) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1906288 0.91 P2RY1 (0.74) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL1906291 0.91 P2RY1 (0.74) DNPH1P2RY1TAS1R3TAS1R1P2RY2
Thioinosine Monophosphate SCHEMBL6368891 0.91 ADORA1 (0.68) DNPH1P2RY1TAS1R3TAS1R1P2RY2
SCHEMBL3859612 0.90 P2RY1 (0.67) DNPH1P2RY1TAS1R3TAS1R1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295671-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2025-09-25 US claimed
US-12357642-B2 Hazardous agent injection system ANTARES PHARMA, INC. (US) 2025-07-15 US claimed
EP-4427737-A2 HAZARDOUS AGENT INJECTION SYSTEM Antares Pharma, Inc. (US) 2024-09-11 EP claimed
US-20230104341-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2023-04-06 US claimed
US-11497753-B2 Hazardous agent injection system ANTARES PHARMA, INC. (US) 2022-11-15 US claimed
US-20200163975-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2020-05-28 US claimed
US-20170361021-A1 Hazardous Agent Injection System ANTARES PHARMA, INC. (US) 2017-12-21 US claimed
US-20170043093-A1 Hazardous Agent Injection System ASSERTIO SPECIALTY PHARMACEUTICALS, LLC 2017-02-16 US claimed
US-20150119799-A1 Hazardous Agent Injection System ASSERTIO SPECIALTY PHARMACEUTICALS, LLC 2015-04-30 US claimed
WO-2014165136-A1 CONSTANT VOLUME PREFILLED SYRINGES AND KITS THEREOF ANTARES PHARMA, INC. (US) 2014-10-09 WO claimed
EP-2408493-A1 HAZARDOUS AGENT INJECTION SYSTEM Antares Pharma, Inc. (US) 2012-01-25 EP claimed
WO-2010108116-A1 HAZARDOUS AGENT INJECTION SYSTEM ANTARES PHARMA, INC. (US) 2010-09-23 WO claimed
US-12629483-B2 Syringe shock absorber for use in an injection device ANTARES PHARMA, INC. (US) 2026-05-19 US disclosed
US-12629482-B2 Syringe shock absorber for use in an injection device ANTARES PHARMA, INC. (US) 2026-05-19 US disclosed
US-12576213-B2 Multiple dosage injector with rack and pinion dosage system having ram that includes a lockout protrusion ANTARES PHARMA, INC. (US) 2026-03-17 US disclosed
US-20260034313-A1 SYRINGE SHOCK ABSORBER FOR USE IN AN INJECTION DEVICE ANTARES PHARMA, INC. (US) 2026-02-05 US disclosed
US-6355623-B2 DETERMINING THE LEVEL OF 6-THIOGUANINE METABOLITE WHEREIN A LEVEL OF 6-THIOGUANINE LESS THAN ABOUT 230 PMOL PER 8 X 108 RED BLOOD CELLS INDICATES A DRUG INCREASE; A LEVEL OF 400PMOL INDICATES A DECREASE; NONTOXIC HOPITAL-SAINTE-JUSTINE (CA) 2002-03-12 US disclosed
EP-1115403-A1 OPTIMIZED USE OF 6-MERCAPTOPURINE DRUG IN THE TREATMENT OF IMMUNE-MEDIATED GASTROINTESTINAL DISORDERS Hospital Sainte-Justine (CA) 2001-07-18 EP disclosed
US-20010006970-A1 Determining the level of 6-thioguanine metabolite wherein a level of 6-thioguanine less than about 230 pmol per 8 x 108 red blood cells indicates a drug increase; a level of 400pmol indicates a decrease; nontoxic HOPITAL SAINTE-JUSTINE 2001-07-05 US disclosed
WO-2000016780-A1 OPTIMIZED USE OF 6-MERCAPTOPURINE DRUG IN THE TREATMENT OF IMMUNE-MEDIATED GASTROINTESTINAL DISORDERS HOPITAL SAINTE-JUSTINE (CA) 2000-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170043093-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20230104341-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-12576213-B2 Multiple dosage injector with rack and pinion dosage system having ram that includes a lockout protrusion RACK1, DYNLL1, TRAF6 DNPH1 3538/4885P2RY1 944/4885TAS1R3 1340/4885
US-20150119799-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-11497753-B2 Hazardous agent injection system TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20250295671-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20170361021-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-20260034313-A1 SYRINGE SHOCK ABSORBER FOR USE IN AN INJECTION DEVICE CRH, SSTR5, CLPP DNPH1 2917/4885P2RY1 794/4885TAS1R3 3147/4885
US-12629482-B2 Syringe shock absorber for use in an injection device SLC6A4, SLC47A2, ABCB11 DNPH1 4076/4885P2RY1 1026/4885TAS1R3 2425/4885
US-12629483-B2 Syringe shock absorber for use in an injection device SLC6A4, SSTR4, SLC6A2 DNPH1 3130/4885P2RY1 486/4885TAS1R3 3035/4885
US-20200163975-A1 Hazardous Agent Injection System TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885
US-12357642-B2 Hazardous agent injection system TIAL1, AHSA1, GYS2 DNPH1 505/4885P2RY1 613/4885TAS1R3 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.