SCHEMBL3794136

SCHEMBL3794136

Cc1ccccc1N(CC(O)CS(=O)(=O)O)CC(O)CS(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PER2 O15055 3/20 0.44
CRY1 Q16526 3/20 0.44
CRY2 Q49AN0 3/20 0.44
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
APEX1 P27695 1/20 0.35
ESR1 P03372 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
LMNA P02545 3/20 0.34
CYP3A4 P08684 2/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL5140869 0.98 PER2 (0.43) PER2CRY1CRY2ALDH1A1MAPT
SCHEMBL6253134 0.93 PER2 (0.41) PER2CRY1CRY2ALDH1A1MAPT
SCHEMBL29813257 0.79 PER2 (0.40) PER2CRY1CRY2ALDH1A1MAPT
SCHEMBL27700093 0.76 PER2 (0.34) PER2CRY1CRY2ALDH1A1ESR1
SCHEMBL242395 0.75 TSHR (0.42) PER2CRY1CRY2ALDH1A1HPGD
SCHEMBL28751431 0.75 CYP3A4 (0.38) PER2CRY1CRY2MAPTNPSR1
SCHEMBL83497 0.74 TRPM8 (0.40) PER2CRY1CRY2LMNACYP3A4
SCHEMBL1374165 0.74 ATM (0.42) PER2CRY1CRY2ALDH1A1MAPT
SCHEMBL6129999 0.73 APEX1 (0.34) PER2CRY1CRY2ALDH1A1MAPT
SCHEMBL6253130 0.71 CNR2 (0.43) ALDH1A1MAPTHPGDHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814669-B2 Blood sample assay method Abbott Rapid Diagnostics International Unlimited Company (IE) 2023-11-14 US disclosed
US-20210332410-A1 BLOOD SAMPLE ASSAY METHOD Abbott Rapid Diagnostics International Unlimited Company (IE) 2021-10-28 US disclosed
US-11085066-B2 Blood sample assay method AXIS-SHIELD AS (NO) 2021-08-10 US disclosed
EP-3473715-B1 CATALASE INHIBITOR AND METHOD FOR MEASURING ANALYTE USING CATALASE INHIBITOR PHC HOLDINGS CORP (JP) 2021-08-04 EP disclosed
US-10702503-B2 Catalase inhibitor and method for measuring analyte using catalase inhibitor PHC HOLDINGS CORPORATION (JP) 2020-07-07 US disclosed
US-20200131560-A1 BLOOD SAMPLE ASSAY METHOD Abbott Rapid Diagnostics International Unlimited Company (IE) 2020-04-30 US disclosed
US-20190321335-A1 CATALASE INHIBITOR AND METHOD FOR MEASURING ANALYTE USING CATALASE INHIBITOR PHC HOLDINGS CORPORATION (JP) 2019-10-24 US disclosed
EP-3473715-A1 CATALASE INHIBITOR AND METHOD FOR MEASURING ANALYTE USING CATALASE INHIBITOR PHC Holdings Corporation (JP) 2019-04-24 EP disclosed
EP-3435089-A1 DETERMINATION OF NON-HDL CHOLESTEROL IN BLOOD Axis-Shield AS (NO) 2019-01-30 EP disclosed
EP-2751575-B1 BLOOD SAMPLE ASSAY METHOD AXIS SHIELD AS (NO) 2018-09-12 EP disclosed
US-20170349933-A1 BLOOD SAMPLE ASSAY METHOD AXIS-SHIELD AS (NO) 2017-12-07 US disclosed
US-9695464-B2 Blood sample assay method AXIS-SHIELD AS (NO) 2017-07-04 US disclosed
US-20140302540-A1 BLOOD SAMPLE ASSAY METHOD Abbott Rapid Diagnostics International Unlimited Company (IE) 2014-10-09 US disclosed
EP-2235543-A1 METHOD TO DETERMINE LIPIDS Axis-Shield Asa (NO) 2010-10-06 EP disclosed
WO-2009081140-A1 METHOD TO DETERMINE LIPIDS AXIS-SHIELD ASA (NO) 2009-07-02 WO disclosed
US-7054514-B2 Optical waveguide sensor, device, system and method for glucose measurement KABUSHIKI KAISHA TOSHIBA (JP) 2006-05-30 US disclosed
US-20050147342-A1 Optical waveguide sensor, device, system and method for glucose measurement KABUSHIKI KAISHA TOSHIBA (JP) 2005-07-07 US disclosed
US-6903815-B2 Optical waveguide sensor, device, system and method for glucose measurement KABUSHIKI KAISHA TOSHIBA (JP) 2005-06-07 US disclosed
US-20030225322-A1 Optical waveguide sensor, device, system and method for glucose measurement KABUSHIKI KAISHA TOSHIBA (JP) 2003-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10702503-B2 Catalase inhibitor and method for measuring analyte using catalase inhibitor CAT, MPO, SOD1 PER2 3082/4885CRY1 1296/4885CRY2 2777/4885
US-20190321335-A1 CATALASE INHIBITOR AND METHOD FOR MEASURING ANALYTE USING CATALASE INHIBITOR CAT, MPO, SOD1 PER2 3082/4885CRY1 1296/4885CRY2 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.